Molecular structure of CB 65, CAS Number: 913534-05-1
CB 65 (CAS 913534-05-1)
Alternate Names:
N-Cyclohexyl-7-chloro-1-[2-(4-morpholinyl)ethyl]quinolin-4(1H)-one-3-carboxamide
Application:
CB 65 is a high affinity and selective cannabinoid CB2 receptor agonist
CAS Number:
913534-05-1
Molecular Weight:
417.93
Molecular Formula:
C22H28ClN3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
CB 65 is a high affinity and selective CB2 receptor agonist Ki values are 3.3 and > 1000 nM for CB2 and CB1 receptors respectively. CB 65 is a research compound with a molecular formula of C22H28ClN3O3 and a molecular weight of 417.9 g/mol. The compound′s exact mass and complexity rating remain unknown.
CB 65 (CAS 913534-05-1) References
- Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists. | Manera, C., et al. 2006. J Med Chem. 49: 5947-57. PMID: 17004710
- The role of central CB2 cannabinoid receptors on food intake in neonatal chicks. | Emadi, L., et al. 2011. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 197: 1143-7. PMID: 21927979
- Evaluation of anti-invasion effect of cannabinoids on human hepatocarcinoma cells. | Pourkhalili, N., et al. 2013. Toxicol Mech Methods. 23: 120-6. PMID: 22978792
- Role of cannabinoid and vanilloid receptors in invasion of human breast carcinoma cells. | Farsandaj, N., et al. 2012. J Environ Pathol Toxicol Oncol. 31: 377-87. PMID: 23394450
- Suppression of outward K⁺ currents by WIN55212-2 in rat retinal ganglion cells is independent of CB1/CB2 receptors. | Zhang, CQ., et al. 2013. Neuroscience. 253: 183-93. PMID: 24013008
- Endocannabinoid and nitric oxide interaction mediates food intake in neonatal chicken. | Hassanpour, S., et al. 2015. Br Poult Sci. 56: 443-51. PMID: 26053311
- Cannabinoid-glutamate interactions in the regulation of food intake in neonatal layer- type chicks: role of glutamate NMDA and AMPA receptors. | Keyshams, N., et al. 2016. Vet Res Commun. 40: 63-71. PMID: 27000110
- Consequence of dopamine D2 receptor blockade on the hyperphagic effect induced by cannabinoid CB1 and CB2 receptors in layers. | Khodadadi, M., et al. 2017. Br Poult Sci. 58: 585-593. PMID: 28728428
- Expression of cannabinoid 1 and, 2 receptors and the effects of cannabinoid 1 and, 2 receptor agonists on detrusor overactivity associated with bladder outlet obstruction in rats. | Kim, SD., et al. 2017. BMC Urol. 17: 121. PMID: 29284441
Activator of:
CB2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CB 65, 10 mg | sc-361134 | 10 mg | $354.00 | |||
CB 65, 50 mg | sc-361134A | 50 mg | $988.00 |