Molecular structure of CAY10626, CAS Number: 1202884-94-3
CAY10626 (CAS 1202884-94-3)
Alternate Names:
N-[2-(dimethylamino)ethyl]-N-methyl-4-[[[[4-[4-(4-morpholinyl)-7-(2,2,2-trifluoroethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]phenyl]amino]carbonyl]amino]-benzamide
CAS Number:
1202884-94-3
Molecular Weight:
624.7
Molecular Formula:
C31H35F3N8O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3′ hydroxyl position of PIs to produce PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3, important second messengers that modulate the activity of downstream targets Akt and mTOR. Aberrent PI3K/Akt is associated with many human cancers. CAY10626 is a potent, dual PI3Kα/mTOR inhibitor with IC50 values of 0.9 and 0.6 nM for the two respective kinases.In a tumor cell growth inhibition assay, CAY10626 demonstrates IC50 values of
CAY10626 (CAS 1202884-94-3) References
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- A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage. | Li, J., et al. 2022. NAR Genom Bioinform. 4: lqac065. PMID: 36110898
Inhibitor of:
mTOR, PI 3-kinase p110 alpha, and XAGE-1C.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CAY10626, 1 mg | sc-358741 | 1 mg | $169.00 | |||
CAY10626, 5 mg | sc-358741A | 5 mg | $756.00 |