Molecular structure of Catharanthine tartrate, CAS Number: 4168-17-6
Catharanthine tartrate (CAS 4168-17-6)
Application:
Catharanthine tartrate is a precursor for synthesis of vinblastine and vincristine
CAS Number:
4168-17-6
Molecular Weight:
486.5
Molecular Formula:
C21H24N2O2•C4H6O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Catharanthine tartrate is the starting material for the synthesis of the antitumor drugs vinblastine and vincristine. It is less active as an inhibitor of tubulin self-assembly into microtubules than the latter two compounds.
Catharanthine tartrate (CAS 4168-17-6) References
- Synthesis and structure-activity relationship studies of cytotoxic ester and ether anhydrovinblastine derivatives. | Zhang, HK., et al. 2008. J Nat Prod. 71: 1669-76. PMID: 18771244
- Synthesis and structure-activity relationship studies of cytotoxic anhydrovinblastine amide derivatives. | Shao, Y., et al. 2009. J Nat Prod. 72: 1170-7. PMID: 19499938
- Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline. | Prakash, V. and Timasheff, SN. 1991. Biochemistry. 30: 873-80. PMID: 1988072
- Photochemical one-pot synthesis of vinblastine and vincristine. | Pennanen, S. and Huhtikangas, A. 1990. Photochem Photobiol. 51: 515-8. PMID: 2367548
- Antimicrobial Activity of Tannin Extract Ointment Formulated from Catharanthus roseus (L.) G. Don Leaves on Infected Wounds of Oryctolagus cuniculus Linn. | Aquino, Mercedita S. 2014. Liceo Journal of Higher Education Research. 10.1: 34-46.
- On Median-Based Discriminant Analysis. | Padua, Roberto N. and Rogelio C. Golez Jr. 2014. Liceo Journal of Higher Education Research. 10.1: 1-19.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Catharanthine tartrate, 100 mg | sc-202524 | 100 mg | $109.00 | |||
Catharanthine tartrate, 1 g | sc-202524A | 1 g | $294.00 |