Molecular structure of Catharanthine base, CAS Number: 2468-21-5
Catharanthine base (CAS 2468-21-5)
Alternate Names:
(+)-3,4-Didehydrocoronaridine
Application:
Catharanthine base is an alkaloids present in Catharanthus roseus
CAS Number:
2468-21-5
Purity:
≥98%
Molecular Weight:
336.43
Molecular Formula:
C21H24N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Catharanthine base is one of the many alkaloids present in Catharanthus roseus. Can be used as a starting material for the synthesis of the anti-tumor drugs vinblastine and vincristine. Catharanthine base is less active as an inhibitor of tubulin self-assembly into microtubules than the latter two compounds.
Catharanthine base (CAS 2468-21-5) References
- Symmetry C18 column: a better choice for the analysis of indole alkaloids of Catharanthus roseus. | Uniyal, GC., et al. 2001. Phytochem Anal. 12: 206-10. PMID: 11705028
- Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline. | Prakash, V. and Timasheff, SN. 1991. Biochemistry. 30: 873-80. PMID: 1988072
- Synthesis and study of a molecularly imprinted polymer for the specific extraction of indole alkaloids from Catharanthus roseus extracts. | Lopez, C., et al. 2011. Anal Chim Acta. 683: 198-205. PMID: 21167971
- Photochemical one-pot synthesis of vinblastine and vincristine. | Pennanen, S. and Huhtikangas, A. 1990. Photochem Photobiol. 51: 515-8. PMID: 2367548
- Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. | Karhu, E., et al. 2017. J Nat Prod. 80: 2602-2608. PMID: 29043803
- QSAR Classification-Based Virtual Screening Followed by Molecular Docking Identification of Potential COX-2 Inhibitors in a Natural Product Library. | Ai, S., et al. 2019. J Comput Biol. 26: 1296-1315. PMID: 31233340
- Catharanthine Modulates Mesolimbic Dopamine Transmission and Nicotine Psychomotor Effects via Inhibition of α6-Nicotinic Receptors and Dopamine Transporters. | Williams, BM., et al. 2024. ACS Chem Neurosci. 15: 1738-1754. PMID: 38613458
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Catharanthine base, 25 mg | sc-204674 | 25 mg | $150.00 | |||
Catharanthine base, 100 mg | sc-204674A | 100 mg | $377.00 |