Date published: 2025-10-2

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(−)-Catechin gallate (CAS 130405-40-2)

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Alternate Names:
(2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate)
Application:
(−)-Catechin gallate is an inhibitor of VEGF-induced tyrosine phosphorylation
CAS Number:
130405-40-2
Purity:
≥98%
Molecular Weight:
442.37
Molecular Formula:
C22H18O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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An antioxidant constituent of green tea. At µM concentrations, inhibits VEGF-induced tyrosine phosphorylation. Also inhibits aromatase activity, an enzyme that converts androgens to estrogen. A major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor.


(−)-Catechin gallate (CAS 130405-40-2) References

  1. Potentiation of catechin gallate-mediated sensitization of Staphylococcus aureus to oxacillin by nongalloylated catechins.  |  Stapleton, PD., et al. 2006. Antimicrob Agents Chemother. 50: 752-5. PMID: 16436737
  2. Determination of extractability of pine bark using supercritical CO(2) extraction and different solvents: optimization and prediction.  |  Yesil-Celiktas, O., et al. 2009. J Agric Food Chem. 57: 341-7. PMID: 19113873
  3. A facile inhibitor screening of SARS coronavirus N protein using nanoparticle-based RNA oligonucleotide.  |  Roh, C. 2012. Int J Nanomedicine. 7: 2173-9. PMID: 22619553
  4. Green Tea Catechins, (-)-Catechin Gallate, and (-)-Gallocatechin Gallate are Potent Inhibitors of ABA-Induced Stomatal Closure.  |  Sato, K., et al. 2022. Adv Sci (Weinh). 9: e2201403. PMID: 35524639
  5. An In Vitro Catalysis of Tea Polyphenols by Polyphenol Oxidase.  |  Liu, K., et al. 2023. Molecules. 28: PMID: 36838710
  6. A study on the change of enantiomeric purity of catechins in green tea infusion  |  Ito, R., Yamamoto, A., Kodama, S., Kato, K., Yoshimura, Y., Matsunaga, A., & Nakazawa, H. 2003. Food chemistry. 83(4): 563-568.
  7. A comparative study of flavonoid contents and antioxidant activities of supercritical CO 2 extracted pine barks grown in different regions of Turkey and Germany  |  Yesil-Celiktas, O., Otto, F., & Parlar, H. 2009. European Food Research and Technology. 229: 671-677.
  8. Catechin gallate a promising resistance modifying candidate to potentiate β-lactam antibiotics to overcome resistance in Staphylococcus aureus  |  Singhal, D., & Saxena, S. 2017. Current Medicine Research and Practice. 7(6): 224-228.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(−)-Catechin gallate, 1 mg

sc-252549
1 mg
$82.00