CAT-1 Antibody (2B9): sc-293226
- CAT-1 Antibody (2B9) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 100 µg/ml
- raised against a partial recombinant protein mapping within amino acids 431-492 of CAT-1 of human origin
- recommended for detection of CAT-1 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CAT-1 Antibody (2B9). This work is in progress.
CAT-1 Antibody (2B9) is a mouse monoclonal IgG1 antibody that detects CAT-1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). CAT-1, also known as high-affinity cationic amino acid transporter-1, plays a crucial role in the transport of cationic amino acids across cell membranes, which is vital for various physiological processes, including protein synthesis and cellular signaling. The proper functioning of CAT-1 is particularly important in non-hepatic tissues, where CAT-1 facilitates the uptake of essential amino acids necessary for cell growth and metabolism. Additionally, CAT-1 has been implicated as a potential receptor for ecotropic retroviruses, highlighting CAT-1′s significance in both normal physiology and viral pathogenesis. The gene encoding CAT-1, SLC7A1, is located on chromosome 13q12-q14, and SLC7A1 expression is tightly regulated, reflecting CAT-1′s importance in maintaining cellular homeostasis. With CAT-1 Antibody (2B9)′s ability to provide insights into both amino acid transport and viral interactions, anti-CAT-1 antibody (2B9) serves as an invaluable tool for researchers studying these critical biological processes.
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CAT-1 Antibody (2B9) References:
- Catalase-1 (CAT-1) and nucleoside diphosphate kinase-1 (NDK-1) play an important role in protecting conidial viability under light stress in Neurospora crassa. | Wang, N., et al. 2007. Mol Genet Genomics. 278: 235-42. PMID: 17636331
- Involvement of OS-2 MAP kinase in regulation of the large-subunit catalases CAT-1 and CAT-3 in Neurospora crassa. | Yamashita, K., et al. 2007. Genes Genet Syst. 82: 301-10. PMID: 17895581
- Temporal regulation of Cat-1 (cationic amino acid transporter-1) gene transcription during endoplasmic reticulum stress. | Huang, CC., et al. 2010. Biochem J. 429: 215-24. PMID: 20408811
- CAT-1-mediated arginine uptake and regulation of nitric oxide synthases for the survival of human breast cancer cell lines. | Abdelmagid, SA., et al. 2011. J Cell Biochem. 112: 1084-92. PMID: 21308737
- The adaptor protein and Arf GTPase-activating protein Cat-1/Git-1 is required for cellular transformation. | Yoo, SM., et al. 2012. J Biol Chem. 287: 31462-70. PMID: 22807447
- CAT-1 as a novel CAM stabilizes endothelial integrity and mediates the protective actions of L-Arg via a NO-independent mechanism. | Guo, L., et al. 2015. J Mol Cell Cardiol. 87: 180-91. PMID: 26283571
- The CAT-1 is out of the bag: endothelial Cationic Amino Acid Transporter-1 is a critical player in cardiorenal syndrome type 2. | Hutchens, MP. and De Miguel, C. 2021. Clin Sci (Lond). 135: 105-108. PMID: 33404050
- Fermentation of D-xylose to Ethanol by Saccharomyces cerevisiae CAT-1 Recombinant Strains. | Coimbra, L., et al. 2023. Bioenergy Res. 16: 1001-1012. PMID: 36248719
- Cationic amino acid transporter-1 (CAT-1) promotes fibroblast-like synoviocyte proliferation and cytokine secretion by taking up L-arginine in rheumatoid arthritis. | Lu, Y., et al. 2022. Arthritis Res Ther. 24: 234. PMID: 36253807
- Adaptive regulation of the cationic amino acid transporter-1 (Cat-1) in Fao cells. | Hyatt, SL., et al. 1997. J Biol Chem. 272: 19951-7. PMID: 9242663
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CAT-1 Antibody (2B9) | sc-293226 | 100 µg/ml | $322.00 |