caspase-3 inhibitor: sc-3073
- Ac-DEVD-cho, Inhibits caspases-3,6,7,8,10
- supplied as 1 mg (lyophilized)
- Store lyophilized caspase-3 inhibitor at -20° C. Stable for at least one year from the date of shipment. Once resuspended, store at 4° C for short term storage or -80° C for long term storage. Avoid repeated freeze/thaw cycles.
- Resuspend caspase-3 inhibitor in 100 µl of sterile water. Resuspension of the caspase-3 inhibitor in 100 µl of sterile water makes a 5 mg/ml solution.
QUICK LINKS
Caspase-3 inhibitors play a crucial role in the exploration of apoptosis, a form of programmed cell death essential for cellular homeostasis and development. Caspase-3, a key executioner enzyme in the apoptosis pathway, is the focus of intensive research to understand its mechanistic roles in cellular processes. Inhibiting caspase-3 allows researchers to dissect the apoptosis signaling pathways, providing insights into the execution phase of cell death where caspase-3 cleaves various cellular substrates, leading to morphological changes and ultimately cell demise. Caspase-3 inhibitors are utilized to study the enzyme′s impact on non-apoptotic roles such as differentiation, proliferation, and gene expression. This investigative approach helps in elucidating how caspase-3 activity affects neuronal development, stem cell differentiation, and tumor suppression. In the broader context of cell signaling, these inhibitors are essential for studying the interplay between apoptosis and other cell death pathways like necroptosis and ferroptosis. By selectively blocking caspase-3, researchers can isolate and analyze specific contributions of this protease to cellular outcomes, enhancing our understanding of cellular resilience and response mechanisms under various stress conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
caspase-3 inhibitor | sc-3073 | 1 mg | $95.00 |