Molecular structure of (+)-Carvone, CAS Number: 2244-16-8
(+)-Carvone (CAS 2244-16-8)
See product citations (2)
Alternate Names:
(S)-(+)-Carvone
Application:
(+)-Carvone is a terpene standard for gas chromatography
CAS Number:
2244-16-8
Purity:
≥95%
Molecular Weight:
150.22
Molecular Formula:
C10H14O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(+)-Carvone, a natural compound extracted from the essential oils of plants. As a cyclic monoterpene ketone, it serves as a flavor and fragrance component in the food and cosmetics industries and as insect repellent. In vitro investigations (+)-Carvone has been explored for its effects on cellular processes encompassing cell growth, differentiation, and apoptosis. Although the exact mechanism of action for (+)-Carvone remains incompletely understood, existing evidence suggests that it functions as an inhibitor of cyclooxygenase-2 (COX-2). Additionally, it is believed to act as an inhibitor of acetylcholinesterase, an enzyme involved in the breakdown of acetylcholine.
(+)-Carvone (CAS 2244-16-8) References
- Stereoselective metabolism of the monoterpene carvone by rat and human liver microsomes. | Jäger, W., et al. 2000. J Pharm Pharmacol. 52: 191-7. PMID: 10714949
- Detection and discrimination of carvone enantiomers in rats with olfactory bulb lesions. | Slotnick, B. and Bisulco, S. 2003. Neuroscience. 121: 451-7. PMID: 14522003
- Influence of the chirality of (R)-(-)- and (S)-(+)-carvone in the central nervous system: a comparative study. | de Sousa, DP., et al. 2007. Chirality. 19: 264-8. PMID: 17299731
- Distinct effects of carvone analogues on the isolated nerve of rats. | Gonçalves, JC., et al. 2010. Eur J Pharmacol. 645: 108-12. PMID: 20670618
- Enantioselective penetration enhancing effect of carvone on the in vitro transdermal permeation of nicorandil. | Krishnaiah, YS. and Nada, A. 2012. Pharm Dev Technol. 17: 574-82. PMID: 21428701
- S-carvone suppresses cellulase-induced capsidiol production in Nicotiana tabacum by interfering with protein isoprenylation. | Huchelmann, A., et al. 2014. Plant Physiol. 164: 935-50. PMID: 24367019
- Spontaneous L-glutamate release enhancement in rat substantia gelatinosa neurons by (-)-carvone and (+)-carvone which activate different types of TRP channel. | Kang, Q., et al. 2015. Biochem Biophys Res Commun. 459: 498-503. PMID: 25747716
- Antimanic-like effects of (R)-(-)-carvone and (S)-(+)-carvone in mice. | Nogoceke, FP., et al. 2016. Neurosci Lett. 619: 43-8. PMID: 26970377
- BITC and S-Carvone Restrain High-Fat Diet-Induced Obesity and Ameliorate Hepatic Steatosis and Insulin Resistance. | Alsanea, S. and Liu, D. 2017. Pharm Res. 34: 2241-2249. PMID: 28733781
- Biotransformation of (+)-Carvone and (-)-Carvone by the Common Cutworm Spodoptera litura Larvae. | Marumoto, S., et al. 2018. J Oleo Sci. 67: 1253-1257. PMID: 30210079
- Effects of (S)-Carvone and Gibberellin on Sugar Accumulation in Potatoes during Low Temperature Storage. | Xie, Y., et al. 2018. Molecules. 23: PMID: 30487439
- Nanoengineered Sorbents To Increase the Persistence of the Allelochemical Carvone in the Rhizosphere. | Gámiz, B., et al. 2019. J Agric Food Chem. 67: 589-596. PMID: 30562019
- Elucidation of the Mechanism Underlying the Anti-Inflammatory Properties of (S)-(+)-Carvone Identifies a Novel Class of Sirtuin-1 Activators in a Murine Macrophage Cell Line. | Sousa, C., et al. 2021. Biomedicines. 9: PMID: 34356841
- Using (+)-Carvone to access novel derivatives of (+)-ent-Cannabidiol: the first asymmetric syntheses of (+)-ent-CBDP and (+)-ent-CBDV. | Golliher, AE., et al. 2021. Tetrahedron Lett. 67: PMID: 34658452
- Gram-Scale Synthesis of Loganetin from S-(+)-Carvone. | Zhuang, X., et al. 2023. J Org Chem. 88: 5844-5851. PMID: 37026980
Inhibitor of:
4832428D23Rik, CXorf34, Olfr402, Olfr812, OR2J3, OR5L1, OR5R1, OR6B3, and V3R 1.Activator of:
Olfr1052, Olfr541, Olfr547, Olfr55, Olfr583, Olfr611, Olfr694, Olfr746, Olfr872, Olfr873, Olfr90, Olfr902, Olfr955, Olfr976, Olfr978, Olfr979, Olfr985, and OR10W1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-Carvone, 5 ml | sc-239480 | 5 ml | $32.00 | |||
(+)-Carvone, 25 ml | sc-239480A | 25 ml | $82.00 |