Date published: 2025-12-1

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Carveol (CAS 99-48-9)

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Alternate Names:
p-Mentha-1,8-dien-6-ol
Application:
Carveol is a terpene that inhibits mammary carcinogenesis
CAS Number:
99-48-9
Purity:
≥96%
Molecular Weight:
152.23
Molecular Formula:
C10H16O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Carveol is a mixture of isomers. A terpene that inhibits mammary carcinogenesis. It is a sesquiterpene lactone and has shown to be a strpng fluorescence probe for the detection of DNA. A naturally unsaturated monocyclic monoterpenoid alchohol that is a component of spearmint essential oil. Used as a fragrance in cosmetics.


Carveol (CAS 99-48-9) References

  1. Metabolism of carveol and dihydrocarveol in Rhodococcus erythropolis DCL14.  |  van der Werf, MJ. and Boot, AM. 2000. Microbiology (Reading). 146 (Pt 5): 1129-1141. PMID: 10832640
  2. Chemoprevention of mammary carcinogenesis by hydroxylated derivatives of d-limonene.  |  Crowell, PL., et al. 1992. Carcinogenesis. 13: 1261-4. PMID: 1638695
  3. Inhibition of human α7 nicotinic acetylcholine receptors by cyclic monoterpene carveol.  |  Lozon, Y., et al. 2016. Eur J Pharmacol. 776: 44-51. PMID: 26849939
  4. Hydroxyl Group and Vasorelaxant Effects of Perillyl Alcohol, Carveol, Limonene on Aorta Smooth Muscle of Rats.  |  Cardoso-Teixeira, AC., et al. 2018. Molecules. 23: PMID: 29899230
  5. Relaxant Effect of Monoterpene (-)-Carveol on Isolated Human Umbilical Cord Arteries and the Involvement of Ion Channels.  |  Evaristo Rodrigues da Silva, R., et al. 2020. Molecules. 25: PMID: 32527034
  6. Potent Natural Antioxidant Carveol Attenuates MCAO-Stress Induced Oxidative, Neurodegeneration by Regulating the Nrf-2 Pathway.  |  Malik, I., et al. 2020. Front Neurosci. 14: 659. PMID: 32714135
  7. Computational and Pharmacological Evaluation of Carveol for Antidiabetic Potential.  |  Ahmed, MS., et al. 2020. Front Pharmacol. 11: 919. PMID: 32848717
  8. Carveol a Naturally-Derived Potent and Emerging Nrf2 Activator Protects Against Acetaminophen-Induced Hepatotoxicity.  |  Rahman, ZU., et al. 2020. Front Pharmacol. 11: 621538. PMID: 33597885
  9. Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole-Kindled Epileptic Rats by Regulating the Nrf2 Signaling Pathway.  |  Alvi, AM., et al. 2021. Oxid Med Cell Longev. 2021: 9966663. PMID: 34422216
  10. Carveol Promotes Nrf2 Contribution in Depressive Disorders through an Anti-inflammatory Mechanism.  |  Muhammad, AJ., et al. 2022. Oxid Med Cell Longev. 2022: 4509204. PMID: 35295720
  11. RIFM fragrance ingredient safety assessment, carveol, CAS Registry Number 99-48-9.  |  Api, AM., et al. 2022. Food Chem Toxicol. 167 Suppl 1: 113269. PMID: 35817257
  12. Carveol ameliorates mercury-induced oxidative stress, neuroinflammation, and neurodegeneration in a mouse brain.  |  Alattar, A., et al. 2022. Neurotoxicology. 92: 212-226. PMID: 35963490
  13. Ameliorative effect of carveol on scopolamine-induced memory impairment in rats.  |  Latif, K., et al. 2022. Iran J Basic Med Sci. 25: 1504-1512. PMID: 36544525

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Carveol, 5 g

sc-205623
5 g
$92.00

Carveol, 25 g

sc-205623A
25 g
$204.00