Date published: 2026-4-26

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Carlina Oxide (CAS 502-22-7)

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Alternate Names:
2-(3-Phenyl-1-propyn-1-yl)-furan; 2-(3-Phenyl-1-propynyl)-furan
CAS Number:
502-22-7
Molecular Weight:
182.22
Molecular Formula:
C13H10O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Carlina oxide has emerged as a valuable compound in a diverse range of scientific research endeavors. Its applications span across the investigation of metal complex structures, reactivity, and the chemistry of organometallic compounds. Furthermore, it has found utility in the exploration of novel material synthesis, including nanomaterials. The versatility of carlina oxide extends to the exploration of enzymatic mechanisms. Researchers have employed this compound to delve into the intricate workings of enzymes and decipher the mechanisms underlying their catalytic activities. Similarly, the investigation of drug mechanisms has benefitted from the utilization of carlina oxide.


Carlina Oxide (CAS 502-22-7) References

  1. Carlina oxide--a natural polyacetylene from Carlina acaulis (Asteraceae) with potent antitrypanosomal and antimicrobial properties.  |  Herrmann, F., et al. 2011. Planta Med. 77: 1905-11. PMID: 21678234
  2. Methodological approach to determine carlina oxide - a main volatile constituent of Carlina acaulis L. essential oil.  |  Strzemski, M., et al. 2019. Talanta. 191: 504-508. PMID: 30262091
  3. Outstanding insecticidal activity and sublethal effects of Carlina acaulis root essential oil on the housefly, Musca domestica, with insights on its toxicity on human cells.  |  Pavela, R., et al. 2020. Food Chem Toxicol. 136: 111037. PMID: 31816346
  4. Toxicity of Carlina Oxide-A Natural Polyacetylene from the Carlina acaulis Roots-In Vitro and In Vivo Study.  |  Wnorowski, A., et al. 2020. Toxins (Basel). 12: PMID: 32283677
  5. Hemisyntheses and In-silico Study of New Analogues of Carlina Oxide from Carthamus Caeruleus Roots.  |  Mami, IR., et al. 2021. Comb Chem High Throughput Screen. 24: 1503-1513. PMID: 33155891
  6. Lethal and behavioural effects of a green insecticide against an invasive polyphagous fruit fly pest and its safety to mammals.  |  Benelli, G., et al. 2022. Chemosphere. 287: 132089. PMID: 34509765
  7. Bioactivity of Carlina acaulis Essential Oil and Its Main Component towards the Olive Fruit Fly, Bactrocera oleae: Ingestion Toxicity, Electrophysiological and Behavioral Insights.  |  Rizzo, R., et al. 2021. Insects. 12: PMID: 34680649
  8. Comprehensive Evaluation of the Antibacterial and Antifungal Activities of Carlina acaulis L. Essential Oil and Its Nanoemulsion.  |  Rosato, A., et al. 2021. Antibiotics (Basel). 10: PMID: 34943662
  9. Carlina oxide inhibits the interaction of SARS-CoV-2 S glycoprotein with angiotensin-converting enzyme 2.  |  Wnorowska, S., et al. 2022. Ind Crops Prod. 187: 115338. PMID: 35846513
  10. Synthesis of Carlina Oxide Analogues and Evaluation of Their Insecticidal Efficacy and Cytotoxicity.  |  Spinozzi, E., et al. 2023. J Nat Prod.. PMID: 37172063
  11. Encapsulation of Carlina acaulis essential oil and carlina oxide to develop long-lasting mosquito larvicides: microemulsions versus nanoemulsions  |  , et al. (2021). Journal of Pest Science. volume 94,: pages 899–915.
  12. Toxicity of Carlina Oxide-A Natural Polyacetylene from the Carlina acaulis Roots-In Vitro and in Vivo Study  |  by Artur Wnorowski, et al. 2020,. Toxins. 12(4),: 239.
  13. Carlina oxide from Carlina acaulis root essential oil acts as a potent mosquito larvicide  |  G Benelli, R Pavela, R Petrelli, FK Nzekoue… - Industrial Crops and …, 2019 - Elsevier. 1 October 2019,. Industrial Crops and Products. Volume 137,: Pages 356-366.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Carlina Oxide, 10 mg

sc-504695
10 mg
$388.00