Date published: 2025-10-18

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Carboxy Gliclazide (CAS 38173-52-3)

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CAS Number:
38173-52-3
Molecular Weight:
353.39
Molecular Formula:
C15H19N3O5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Carboxy Gliclazide is a chemical derivative of gliclazide, distinguished by its additional carboxyl group, which alters its chemical properties and utility in research. Unlike its parent compound, Carboxy Gliclazide is primarily utilized in scientific studies for its biochemical and pharmacological profiling, focusing on its interaction with various enzymes and receptors at the molecular level. This derivative has been instrumental in elucidating the binding dynamics and inhibition mechanisms on enzyme classes such as hydrolases or transferases, offering insights into enzyme-substrate specificity and the modulation of enzymatic activity through structural alteration of known active agents. In molecular biology research, Carboxy Gliclazide serves as a valuable tool in the study of glucose transporter proteins. Its modified structure allows researchers to track and analyze the transporter activity changes in response to structural variations, aiding in the understanding of glucose uptake mechanisms at a cellular level. Additionally, this compound has been used in studies focused on oxidative stress, providing a model for examining the role of chemical modifications in altering reactive oxygen species (ROS) production and scavenging activities within biological systems. Overall, Carboxy Gliclazide is an important compound in research contexts, particularly for its role in advancing the understanding of molecular interactions and the effects of structural modifications on biological functions.


Carboxy Gliclazide (CAS 38173-52-3) References

  1. Drug-drug Interaction between Pravastatin and Gemfibrozil (Antihyperlipidemic) with Gliclazide (Antidiabetic) in Rats.  |  Sultanpur, C., et al. 2010. J Young Pharm. 2: 152-5. PMID: 21264118
  2. Modeling the effects of commonly used drugs on human metabolism.  |  Sahoo, S., et al. 2015. FEBS J. 282: 297-317. PMID: 25345908
  3. Gliclazide hydroxylation by rat liver microsomes.  |  Rieutord, A., et al. 1995. Xenobiotica. 25: 1345-54. PMID: 8719909
  4. Effect of protease inhibitors (indinavir and ritonavir) on the pharmacokinetics of gliclazide in rabbits  |  Kumar, K. E., & Mastan, S. 2011. Research and Reports in Endocrine Disorders. 1: 1-9.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Carboxy Gliclazide, 10 mg

sc-397658
10 mg
$380.00