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Carboplatin-d4 is a labeled derivative of Carboplatin (sc-202093), a second generation potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of Carboplatin was inspired from the efficacy of its progenitor, Cisplatin (sc-200896), the first of this class of anti-neoplastic agents. Carboplatin displays potent antiproliferative activity and lower nephrotoxicity than Cisplatin. The action of this group of platinum-based compounds is primarily attributed to DNA adduct formation, however, these molecules also bind other biological molecules such as enzymes which might play a role in their mechanism of action.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Carboplatin-d4, 1 mg | sc-217840 | 1 mg | $388.00 |