Carbidopa-d5 (CAS 1185134-76-2)
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Carbidopa-d5 is a deuterium-labeled analog of carbidopa, where five hydrogen atoms are replaced by deuterium. This isotopic labeling is used to improve the detection and quantification of carbidopa in analytical research through methods such as mass spectrometry. In studies, Carbidopa-d5 serves as an internal standard that allows for greater analytical precision due to the minimal differences in chemical behavior between the labeled and non-labeled molecules, while providing a distinguishable mass difference. Research involving Carbidopa-d5 focuses on the compound′s stability, its kinetics, and metabolism. Additionally, it is used in the study of the mechanisms by which carbidopa acts in various biochemical pathways, particularly those relevant to its role in inhibiting aromatic amino acid decarboxylation.
Carbidopa-d5 (CAS 1185134-76-2) References
- Sensitive LC-MS/MS method for quantitation of levodopa and carbidopa in plasma: application to a pharmacokinetic study. | Ferreira, MS., et al. 2018. Bioanalysis. 10: 1567-1576. PMID: 30295551
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Carbidopa-d5, 1 mg | sc-217836 | 1 mg | $337.00 |