Molecular structure of Carbaprostacyclin-biotin
Carbaprostacyclin-biotin
Application:
Carbaprostacyclin-biotin is a relatively indiscriminant ligand for prostaglandin receptors
Molecular Weight:
661.0
Molecular Formula:
C36H60N4O5S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
A structural analog of prostacyclin (PGI2) with about 1/10 the receptor binding affinity of prostacyclin.1 It is a relatively indiscriminant ligand for prostaglandin receptors, binding to all the recombinant human PG receptors, except the TP receptor, with an affinity which is a significant fraction of the natural ligand.2 Carbaprostacyclin-biotinamide is therefore a useful affinity ligand for the binding and purification of a number of different receptors subtypes.
Carbaprostacyclin-biotin References
1 Schrör, K., Darius, H., Matzky, R., et al. The antiplatelet and cardiovascular actions of a new carbacyclin derivative (ZK36374) - equipotent to PGI2 in vitro. Naunyn-Schmiedeberg's Arch Pharmacol 316 252-255 (1981). 2 Abramovitz, M., Adam, M., Boie, Y., et al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483 285-293 (2000).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Carbaprostacyclin-biotin, 100 µg | sc-221394 | 100 µg | $86.00 | |||
Carbaprostacyclin-biotin, 500 µg | sc-221394A | 500 µg | $390.00 |