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Campesterol (CAS 474-62-4)

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Alternate Names:
24α-Methyl-5-cholesten-3β-ol; 24(R)-Ergost-5-en-3β-ol
Application:
Campesterol is a plant sterol used for research purposes
CAS Number:
474-62-4
Purity:
≥95%
Molecular Weight:
400.68
Molecular Formula:
C28H48O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Campesterol is a phytosterol that is of significant interest in plant biology and nutritional studies due to its presence in various plant-based foods. Researchers study campesterol for its role in plant cell membrane structure and function, as sterols are components that modulate membrane fluidity and permeability. In the context of plant physiology, campesterol is also investigated for its involvement in plant growth and development, particularly in the biosynthesis of plant hormones. Additionally, research into campesterol includes its impact on plant stress responses, as sterols can influence the resilience of plants to environmental stresses. Nutritional studies examine the implications of campesterol intake from dietary sources and its effect on human nutrition, given its structural similarity to cholesterol. Studies of campesterol contribute to a broader understanding of both plant biology and the potential implications of dietary phytosterols.


Campesterol (CAS 474-62-4) References

  1. Determination of campesterol, stigmasterol, and beta-sitosterol in saw palmetto raw materials and dietary supplements by gas chromatography: collaborative study.  |  Sorenson, WR. and Sullivan, D. 2007. J AOAC Int. 90: 670-8. PMID: 17580618
  2. Identification of campesterol from Chrysanthemum coronarium L. and its antiangiogenic activities.  |  Choi, JM., et al. 2007. Phytother Res. 21: 954-9. PMID: 17604370
  3. Preferential campesterol incorporation into various tissues in apolipoprotein E*3-Leiden mice consuming plant sterols or stanols.  |  Plat, J., et al. 2008. Metabolism. 57: 1241-7. PMID: 18702950
  4. Oxidation of β-sitosterol and campesterol in sunflower oil upon deep- and pan-frying of French fries.  |  Ramadan, MF. 2015. J Food Sci Technol. 52: 6301-11. PMID: 26396375
  5. Engineering Yarrowia lipolytica for Campesterol Overproduction.  |  Du, HX., et al. 2016. PLoS One. 11: e0146773. PMID: 26751680
  6. Phytosterol content and the campesterol:sitosterol ratio influence cotton fiber development: role of phytosterols in cell elongation.  |  Deng, S., et al. 2016. Sci China Life Sci. 59: 183-93. PMID: 26803301
  7. Ajuga Δ24-Sterol Reductase Catalyzes the Direct Reductive Conversion of 24-Methylenecholesterol to Campesterol.  |  Tsukagoshi, Y., et al. 2016. J Biol Chem. 291: 8189-98. PMID: 26872973
  8. Improved campesterol production in engineered Yarrowia lipolytica strains.  |  Zhang, Y., et al. 2017. Biotechnol Lett. 39: 1033-1039. PMID: 28357621
  9. Oxidation of sitosterol and campesterol in foods upon cooking with liquid margarines without and with added plant sterol esters.  |  Lin, Y., et al. 2018. Food Chem. 241: 387-396. PMID: 28958544
  10. Increased campesterol synthesis by improving lipid content in engineered Yarrowia lipolytica.  |  Qian, YD., et al. 2020. Appl Microbiol Biotechnol. 104: 7165-7175. PMID: 32592029
  11. Disruption of Endoplasmic Reticulum and ROS Production in Human Ovarian Cancer by Campesterol.  |  Bae, H., et al. 2021. Antioxidants (Basel). 10: PMID: 33802602
  12. Molecular docking and dynamic simulations of Ocimum basilicum compounds against HCC and structural, vibrational, quantum, and chemical investigation of campesterol.  |  Sangeetha, R., et al. 2022. J Biomol Struct Dyn. 40: 13997-14012. PMID: 34738880
  13. Relationship between Diabetes Mellitus and Serum Lathosterol and Campesterol Levels: The CACHE Study DM Analysis.  |  Matsumura, T., et al. 2022. J Atheroscler Thromb.. PMID: 36171088
  14. Plasma Campesterol Is Positively Associated with Carotid Plaques in Asymptomatic Subjects.  |  Nunes, VS., et al. 2022. Int J Mol Sci. 23: PMID: 36233298

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Campesterol, 1 mg

sc-214658
1 mg
$146.00

Campesterol, 5 mg

sc-214658A
5 mg
$372.00

I would like to know what the shelf life of this product is before and after dissolved?

Asked by: PRC0331
Thank you for your question. The solid compound has a shelf life of 2 years, though we recommend our customers perform QC every year. Regarding the solution, we recommend to prepare fresh solutions prior to each use.
Answered by: Technical Support
Date published: 2020-05-08

It is possible to obtain MSDS for this product? SC-214658A

Asked by: Paulina
Thank you for your question. You can download an MSDS (SDS) for this chemical, Campesterol (CAS 474-62-4), on our website. There is a tab named "SDS & Certificate Analysis" that is found below the ordering information table on the product page.
Answered by: Technical Support
Date published: 2017-03-30

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. Campesterol, sc-214658, is a white or off-white powder.
Answered by: Chemical Support 4
Date published: 2017-03-10

I would like to know the concrete purity of this product and what is the impurity composition?

Asked by: two2igm05
Thank you for your question. Campesterol, sc-214658, has a purity of 70% determined by TLC.
Answered by: TechService7
Date published: 2017-01-04

What is the shipping condition and regulation of this compound?

Asked by: two2igm05
Thank you for your question. Campesterol, sc214658, can ship at ambient temperature and there are no regulations attributed with the compound.
Answered by: TechService7
Date published: 2017-01-04
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Rated 5 out of 5 by from PlatPlat, J. et al. (PubMed 18702950) reported that in apolipoprotein E*3-Leiden mice, Campesterol is preferentially incorporated into most tissues over sitosterol. -SCBT Publication Review
Date published: 2015-06-07
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Campesterol is rated 5.0 out of 5 by 1.
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