Calretinin Antibody (B-8): sc-365695
- Calretinin Antibody (B-8) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-27 at the N-terminus of Calretinin of human origin
- recommended for detection of Calretinin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine and porcine
- m-IgG3 BP-HRP is the preferred secondary detection reagent for Calretinin Antibody (B-8) for WB and IHC(P) applications. This reagent is now offered in a bundle with Calretinin Antibody (B-8) (see ordering information below).
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Calretinin Antibody (B-8) is a mouse monoclonal IgG3 antibody that detects Calretinin in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Calretinin is a crucial intracellular calcium-binding protein that plays a significant role in calcium signaling within neurons, which is essential for maintaining proper neuronal function and excitability. Calretinin is predominantly located in the brain, particularly in auditory neurons, where anti-Calretinin antibody (B-8) reveals involvement in the precise timing of neuronal discharges, a critical aspect for auditory processing. Calretinin in these neurons is associated with their ability to form synaptic connections that are vital for effective communication between cells. Additionally, Calretinin serves as a valuable immunocytochemical marker for mesothelioma, aiding in the diagnosis and understanding of this cancer type. With specific reactivity and versatile applications, Calretinin (B-8) antibody provides researchers with an indispensable tool for studying calcium signaling and its implications in various neurological conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Calretinin Antibody (B-8) References:
- Calretinin as a diagnostic adjunct for ameloblastoma. | Anandani, C., et al. 2014. Patholog Res Int. 2014: 308240. PMID: 24839578
- The vulnerability of calretinin-containing hippocampal interneurons to temporal lobe epilepsy. | Tóth, K. and Maglóczky, Z. 2014. Front Neuroanat. 8: 100. PMID: 25324731
- Calretinin Participates in Regulating Steroidogenesis by PLC-Ca2+-PKC Pathway in Leydig Cells. | Xu, W., et al. 2018. Sci Rep. 8: 7403. PMID: 29743498
- Immunohistochemical diagnostics of Hirschprungs disease using calretinin. | Marta, J., et al. 2019. Cesk Patol. 55: 53-59. PMID: 30939888
- Calretinin+-neurons-mediated GABAergic inhibition in mouse prefrontal cortex. | Saffari, R., et al. 2019. Prog Neuropsychopharmacol Biol Psychiatry. 94: 109658. PMID: 31145926
- Calretinin-Expressing Synapses Show Improved Synaptic Efficacy with Reduced Asynchronous Release during High-Rate Activity. | Zhang, C., et al. 2022. J Neurosci. 42: 2729-2742. PMID: 35165172
- Calretinin immunohistochemical staining in Hirschsprung's disease: An institutional experience. | Zemheri, E., et al. 2021. North Clin Istanb. 8: 601-606. PMID: 35284789
- Calretinin stain for the accurate diagnosis of atypical Cardiac Myxoma. | Muñiz, ÁM., et al. 2023. Int J Cardiovasc Imaging. 39: 461-462. PMID: 36394681
- Calretinin Staining in Anorectal Line Biopsies Accurately Distinguished Hirschsprung Disease in a Retrospective Study. | Logan, SJ., et al. 2022. Pediatr Dev Pathol. 25: 645-655. PMID: 36408569
- Cortical calretinin-positive neurons: Functional and ontogenetic characteristics and their relationship to brain pathologies. | Vanessa Becerra-Hernández, L., et al. 2025. Brain Res. 1846: 149285. PMID: 39490954
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Calretinin Antibody (B-8) | sc-365695 | 200 µg/ml | $316.00 | |||
Calretinin Antibody (B-8): m-IgG3 BP-HRP Bundle | sc-550437 | 200 µg Ab; 40 µg BP | $354.00 | |||
Calretinin (B-8) Neutralizing Peptide | sc-365695 P | 100 µg/0.5 ml | $68.00 |