Calretinin Antibody (34): sc-135853
- Calretinin Antibody (34) is a mouse monoclonal IgG1, cited in 3 publications, provided at 50 µg/500 µl
- raised against amino acids 38-151 of Calretinin of rat origin
- recommended for detection of Calretinin of mouse, rat and human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Calretinin Antibody (34). This work is in progress.
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Calretinin Antibody (34) is a mouse monoclonal IgG1 light chain antibody that detects Calretinin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Calretinin is a vital intracellular calcium-binding protein that plays a crucial role in calcium signaling within neurons, particularly in the auditory system where Calretinin is abundantly expressed. Calretinin is essential for the precise timing of neuronal discharges, which is critical for auditory processing and communication. Calretinin (34) antibody helps identify specific neuronal populations in the nucleus accumbens associated with unique morphological features, including nuclear indentations, which may influence synaptic plasticity and neuronal connectivity. Calretinin-immunoreactive boutons form both asymmetrical and symmetrical synaptic specializations, indicating Calretinin′s involvement in modulating synaptic transmission and signal integration. Due to distinct expression patterns, anti-Calretinin antibody (34) serves as an invaluable immunocytochemical marker for diagnosing mesothelioma, making Calretinin (34) monoclonal antibody essential for researchers and clinicians studying calcium signaling and its implications in various neurological conditions.
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Calretinin Antibody (34) References:
- Calretinin and other CaBPs in the nervous system. | Rogers, J., et al. 1990. Adv Exp Med Biol. 269: 195-203. PMID: 2191557
- Value of calretinin immunostaining in diagnostic pathology: a review and update. | Ordóñez, NG. 2014. Appl Immunohistochem Mol Morphol. 22: 401-15. PMID: 24185118
- Neocortical calretinin neurons in primates: increase in proportion and microcircuitry structure. | Džaja, D., et al. 2014. Front Neuroanat. 8: 103. PMID: 25309344
- The calretinin interneurons of the striatum: comparisons between rodents and primates under normal and pathological conditions. | Petryszyn, S., et al. 2018. J Neural Transm (Vienna). 125: 279-290. PMID: 28168621
- Calretinin as a blood-based biomarker for mesothelioma. | Johnen, G., et al. 2017. BMC Cancer. 17: 386. PMID: 28558669
- Revealing the Precise Role of Calretinin Neurons in Epilepsy: We Are on the Way. | Qi, Y., et al. 2022. Neurosci Bull. 38: 209-222. PMID: 34324145
- Unraveling the Role of Dopaminergic and Calretinin Interneurons in the Olfactory Bulb. | Capsoni, S., et al. 2021. Front Neural Circuits. 15: 718221. PMID: 34690707
- Serum Calretinin as a Biomarker in Malignant Mesothelioma. | Zupanc, C., et al. 2021. J Clin Med. 10: PMID: 34768395
- Parasubthalamic calretinin neurons modulate wakefulness associated with exploration in male mice. | Guo, H., et al. 2023. Nat Commun. 14: 2346. PMID: 37095092
- Serum Calretinin and Genetic Variability as a Prognostic and Predictive Factor in Malignant Mesothelioma. | Zupanc, C., et al. 2023. Int J Mol Sci. 25: PMID: 38203360
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Calretinin Antibody (34) | sc-135853 | 50 µg/500 µl | $316.00 |