Calindol hydrochloride (CAS 729610-18-8)
See product citations (8)
QUICK LINKS
Calindol hydrochloride functions as a selective serotonin 5-HT1A receptor agonist. It acts by binding to and activating the 5-HT1A receptor, leading to downstream signaling cascades within the cell. This activation modulates the release of neurotransmitters such as serotonin, dopamine, and norepinephrine in the central nervous system. By targeting the 5-HT1A receptor, Calindol hydrochloride may influence neuronal activity and neurotransmitter release, potentially impacting various physiological and behavioral processes. At the molecular level, Calindol hydrochloride′s mechanism of action involves the modulation of intracellular signaling pathways and neurotransmitter release, which may have implications for neurobiology and behavior. Its specific interaction with the 5-HT1A receptor may be a relevant compound for investigating the role of serotonin receptors in neuronal function and behavior.
Calindol hydrochloride (CAS 729610-18-8) References
- Immunohistochemical and functional studies on calcium-sensing receptors in rat uterine smooth muscle. | Pistilli, MJ., et al. 2012. Clin Exp Pharmacol Physiol. 39: 37-42. PMID: 22013999
- The calcimimetic calindol prevents high phosphate-induced vascular calcification by upregulating matrix GLA protein. | Ciceri, P., et al. 2012. Nephron Exp Nephrol. 122: 75-82. PMID: 23548867
- Low-molecular fraction of wheat protein hydrolysate stimulates glucagon-like peptide-1 secretion in an enteroendocrine L cell line and improves glucose tolerance in rats. | Kato, M., et al. 2017. Nutr Res. 37: 37-45. PMID: 28215313
- Involvement of mitochondrial fission in calcium sensing receptor-mediated vascular smooth muscle cells proliferation during hypertension. | Zhang, X., et al. 2018. Biochem Biophys Res Commun. 495: 454-460. PMID: 29128361
- A Forward Genetic Screen in Zebrafish Identifies the G-Protein-Coupled Receptor CaSR as a Modulator of Sensorimotor Decision Making. | Jain, RA., et al. 2018. Curr Biol. 28: 1357-1369.e5. PMID: 29681477
- NLRP3 Inflammasome Is Involved in Calcium-Sensing Receptor-Induced Aortic Remodeling in SHRs. | Zhang, X., et al. 2019. Mediators Inflamm. 2019: 6847087. PMID: 30906225
- Relationship between CaSRs and LPS-injured cardiomyocytes. | Han, G., et al. 2018. Int J Clin Exp Pathol. 11: 1965-1971. PMID: 31938302
- Calcium sensing receptor involving in therapy of embryonic stem cell transplantation alleviates acute myocardial infarction by inhibiting apoptosis and oxidative stress in rats. | Yuan, H., et al. 2020. Iran J Basic Med Sci. 23: 1353-1359. PMID: 33149870
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Calindol hydrochloride, 10 mg | sc-211006 | 10 mg | $408.00 |