Date published: 2025-9-19

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Calcium pyrophosphate (CAS 7790-76-3)

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Alternate Names:
Calcium diphosphate; Dicalcium diphosphate; alpha-Calcium pyrophosphate
CAS Number:
7790-76-3
Purity:
≥99%
Molecular Weight:
254.10
Molecular Formula:
Ca2P2O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Calcium pyrophosphate (CPP) is a multifaceted compound that holds a pivotal position in the realm of scientific research, not just for its structural composition of calcium and pyrophosphate ions but for its dynamic role across various experimental conditions. Its utility extends through serving as a reagent, catalyst, inhibitor, buffer, and chelator, underscoring its versatility and indispensability in facilitating a broad spectrum of biochemical and chemical processes. The interactions between the calcium and pyrophosphate ions within Calcium pyrophosphate are believed to foster a unique complex formation. This formation is instrumental in its function, particularly in catalyzing reactions by providing a conducive environment that accelerates reaction rates or by stabilizing transitional states. Similarly, as an inhibitor, Calcium pyrophosphate′s complex can form interactions that prevent the catalytic activity of certain enzymes or chemical reactions, thereby mitigating the advancement of undesired side-products.


Calcium pyrophosphate (CAS 7790-76-3) References

  1. Differential effect of calcium phosphate and calcium pyrophosphate on binding of matrix metalloproteinases to fibrin: comparison to a fibrin-binding protease from inflammatory joint fluids.  |  Makowski, GS. and Ramsby, ML. 2004. Clin Exp Immunol. 136: 176-87. PMID: 15030529
  2. Osteoarthritis, calcium pyrophosphate deposition disease, and osseous infection in Old World primates.  |  Rothschild, BM. and Woods, RJ. 1992. Am J Phys Anthropol. 87: 341-7. PMID: 1562060
  3. Titanium implant osseointegration with calcium pyrophosphate in rabbits.  |  Koo, S., et al. 2006. J Biomed Mater Res B Appl Biomater. 76: 373-80. PMID: 16184530
  4. Distinguishing erosive osteoarthritis and calcium pyrophosphate deposition disease.  |  Rothschild, BM. 2013. World J Orthop. 4: 29-31. PMID: 23610748
  5. [Deposition of the calcium pyrophosphate crystals on the joint surfaces of the temporo-mandibular joint].  |  Volovar, OS. and Kustr'o, TV. 2013. Klin Khir. 77-9. PMID: 24501976
  6. Methotrexate: should it still be considered for chronic calcium pyrophosphate crystal disease?  |  Pascual, E., et al. 2015. Arthritis Res Ther. 17: 89. PMID: 25885915
  7. Tuberculosis of the Wrist Accompanied with Calcium Pyrophosphate.  |  Watanabe, K., et al. 2017. Intern Med. 56: 3389-3394. PMID: 29021467
  8. [A muscular calcium pyrophosphate deposition pseudo-abscess: An atypical localization of chondrocalcinosis].  |  Oliosi, E., et al. 2019. Rev Med Interne. 40: 211-213. PMID: 30348464
  9. Calcium Pyrophosphate Dihydrate Deposition Disease in Young Patients: Two Case Reports.  |  Wickrematilake, GW. 2017. Arch Rheumatol. 32: 80-83. PMID: 30375521
  10. Calcium pyrophosphate deposition disease after total knee arthroplasty: Comparison with periprosthetic joint infection.  |  Iwasaki, K., et al. 2019. J Orthop. 16: 128-132. PMID: 30890855
  11. Treatment of calcium pyrophosphate deposition in the temporomandibular joint with resection and simultaneous reconstruction using a custom joint prosthesis.  |  Abou-Foul, AK. and Saeed, NR. 2020. Oral Maxillofac Surg. 24: 235-238. PMID: 31845090
  12. Calcium pyrophosphate deposition disease: The role of imaging in their detection and in differential diagnosis of crystal arthropathies.  |  Catelli, A., et al. 2020. Radiol Case Rep. 15: 1773-1776. PMID: 32774579
  13. Accuracy of synovial fluid analysis compared to histology for the identification of calcium pyrophosphate crystals: an ancillary study of the OMERACT US Working Group - CPPD subgroup.  |  Sirotti, S., et al. 2021. Reumatismo. 73: 106-110. PMID: 34342211
  14. Intercostal Muscle Abscesses in Infective Endocarditis Associated With Migratory Deposition of Calcium Pyrophosphate.  |  Nakayama, Y., et al. 2022. Cureus. 14: e21396. PMID: 35198303
  15. Self-assembled calcium pyrophosphate nanostructures for targeted molecular delivery.  |  Bassett, DC., et al. 2022. Biomater Adv. 140: 213086. PMID: 35988368

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Calcium pyrophosphate, 250 g

sc-234270
250 g
$54.00

Calcium pyrophosphate, 1 kg

sc-234270A
1 kg
$108.00

Calcium pyrophosphate, 5 kg

sc-234270B
5 kg
$271.00

Calcium pyrophosphate, 50 kg

sc-234270C
50 kg
$1020.00