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Calcium Ionophore A23187 hemimagnesium salt (CAS 72124-77-7)

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Alternate Names:
A23187 hemimagnesium salt; Antibiotic A 23187 hemimagnesium salt
Application:
Calcium Ionophore A23187 hemimagnesium salt is an Ionophore that is highly selective for Ca+2
CAS Number:
72124-77-7
Molecular Weight:
534.77
Molecular Formula:
C29H36Mg0.5N3O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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An Ionophore that is highly selective for Ca+2. It potentiates responses to NMDA but not quisqualate. In cell culture, this stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.


Calcium Ionophore A23187 hemimagnesium salt (CAS 72124-77-7) References

  1. Nitric oxide as a signal in blood vessels.  |  Knowles, RG. and Moncada, S. 1992. Trends Biochem Sci. 17: 399-402. PMID: 1280869
  2. Calcimycin potentiates responses of rat hippocampal neurons to N-methyl-D-aspartate.  |  Markram, H. and Segal, M. 1991. Brain Res. 540: 322-4. PMID: 2054627
  3. Decreased adhesion to endothelium leads to elevated neutrophil granulocyte count in hereditary angioedema patients.  |  Kajdácsi, E., et al. 2023. Sci Rep. 13: 13366. PMID: 37591965
  4. Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria.  |  Kauffman, RF., et al. 1980. J Biol Chem. 255: 2735-9. PMID: 6766939
  5. Biological applications of ionophores.  |  Pressman, BC. 1976. Annu Rev Biochem. 45: 501-30. PMID: 786156

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Calcium Ionophore A23187 hemimagnesium salt, 5 mg

sc-252540
5 mg
$287.00