Calcium D-(+)-pantothenate (CAS 137-08-6)

Calcium D-(+)-pantothenate, a calcium salt of the D-isomer of pantothenic acid, plays a pivotal role in the biosynthesis of coenzyme A (CoA), a critical cofactor involved in numerous metabolic pathways essential for life. This compound is instrumental in the Krebs cycle, a core energy-yielding process, by facilitating the synthesis of acetyl-CoA, a intermediary that bridges the gap between carbohydrate, fat, and protein metabolism. It also participates in the synthesis and oxidation of fatty acids and the decarboxylation of keto acids, showcasing its versatility and indispensable role in cellular biochemistry. In research, Calcium D-(+)-pantothenate serves as a key nutrient in microbiological culture media, enabling the growth of various microorganisms by supplying essential elements needed for their proliferation. This characteristic makes it invaluable in the study of microbial metabolism and genetics, as well as in the production of antibiotics and other bioactive compounds through fermentation processes. Its role extends beyond mere nutrient support, as it also aids in the elucidation of enzyme mechanisms and the investigation of metabolic pathways, thus contributing to a deeper understanding of cellular and molecular biology.