Date published: 2026-2-20

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Cafestol acetate (CAS 81760-48-7)

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Application:
Cafestol acetate is a glutathione S-transferase inducer
CAS Number:
81760-48-7
Purity:
≥98%
Molecular Weight:
358.47
Molecular Formula:
C22H30O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cafestol acetate acts as a glutathione S-transferase inducer.


Cafestol acetate (CAS 81760-48-7) References

  1. Suppressive effects of the kahweol and cafestol on cyclooxygenase-2 expression in macrophages.  |  Kim, JY., et al. 2004. FEBS Lett. 569: 321-6. PMID: 15225655
  2. Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage.  |  Lee, KJ. and Jeong, HG. 2007. Toxicol Lett. 173: 80-7. PMID: 17689207
  3. Cafestol, a coffee-specific diterpene, induces peripheral antinociception mediated by endogenous opioid peptides.  |  Guzzo, LS., et al. 2012. Clin Exp Pharmacol Physiol. 39: 412-6. PMID: 22332877
  4. Cafestol, a Bioactive Substance in Coffee, Stimulates Insulin Secretion and Increases Glucose Uptake in Muscle Cells: Studies in Vitro.  |  Mellbye, FB., et al. 2015. J Nat Prod. 78: 2447-51. PMID: 26465380
  5. A Combination of Coffee Compounds Shows Insulin-Sensitizing and Hepatoprotective Effects in a Rat Model of Diet-Induced Metabolic Syndrome.  |  Shokouh, P., et al. 2017. Nutrients. 10: PMID: 29271886
  6. Use of silver nitrate impregnated silica cartridges in the separation of kahweol and cafestol esters by preparative liquid chromatography.  |  Lam, LK., et al. 1985. J Chromatogr. 328: 422-4. PMID: 2993334
  7. Cafestol Inhibits High-Glucose-Induced Cardiac Fibrosis in Cardiac Fibroblasts and Type 1-Like Diabetic Rats.  |  Liu, JC., et al. 2020. Evid Based Complement Alternat Med. 2020: 4503747. PMID: 33488743
  8. Characterization of bacterial mutagenicity mediated by 13-hydroxy-ent-kaurenoic acid (steviol) and several structurally-related derivatives and evaluation of potential to induce glutathione S-transferase in mice.  |  Pezzuto, JM., et al. 1986. Mutat Res. 169: 93-103. PMID: 3512998
  9. Therapeutic Potential of Natural Products in the Treatment of Renal Cell Carcinoma: A Review.  |  Feng, C., et al. 2022. Nutrients. 14: PMID: 35684073
  10. Effects of derivatives of kahweol and cafestol on the activity of glutathione S-transferase in mice.  |  Lam, LK., et al. 1987. J Med Chem. 30: 1399-403. PMID: 3612687

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cafestol acetate, 50 mg

sc-205612
50 mg
$235.00

Cafestol acetate, 100 mg

sc-205612A
100 mg
$312.00