CA XIII Antibody (D-8) is a mouse monoclonal IgG1 antibody that detects carbonic anhydrase XIII (CA XIII) in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CA XIII, also known as carbonate dehydratase XIII, belongs to the carbonic anhydrase family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CA XIII (D-8) antibody targets proteins predominantly found in the cytoplasm of cells within the spleen, prostate, thymus, ovary, testis, colon, and small intestine, highlighting CA XIII′s significant role in various physiological processes. CA XIII′s subcellular localization enables effective participation in pH and bicarbonate regulation, which are vital for maintaining acid-base balance in the body. CA XIII shares highest homology with CA I, CA II, and CA III, suggesting potential overlapping functions and interactions within the carbonic anhydrase family. Sulfanilyl-sulfonamide type inhibitors have shown efficient inhibition of CA XIII activity, indicating potential therapeutic applications. Anti-CA XIII antibody (D-8) serves as an essential tool for researchers investigating carbonic anhydrases in health and disease.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CA XIII Antibody (D-8) | sc-374517 | 200 µg/ml | $316.00 | |||
CA XIII Antibody (D-8): m-IgGλ BP-HRP Bundle | sc-522765 | 200 µg Ab, 40 µg BP | $354.00 | |||
CA XIII (D-8) Neutralizing Peptide | sc-374517 P | 100 µg/0.5 ml | $68.00 |