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CA XIII Antibody (D-8): sc-374517

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Datasheets
  • CA XIII Antibody (D-8) is a mouse monoclonal IgG1 (lambda light chain) provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 31-65 within an internal region of CA XIII of human origin
  • recommended for detection of CA XIII of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for CA XIII Antibody (D-8) for WB and IHC(P) applications. This reagent is now offered in a bundle with CA XIII Antibody (D-8) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.

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    CA XIII Antibody (D-8) is a mouse monoclonal IgG1 antibody that detects carbonic anhydrase XIII (CA XIII) in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CA XIII, also known as carbonate dehydratase XIII, belongs to the carbonic anhydrase family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CA XIII (D-8) antibody targets proteins predominantly found in the cytoplasm of cells within the spleen, prostate, thymus, ovary, testis, colon, and small intestine, highlighting CA XIII′s significant role in various physiological processes. CA XIII′s subcellular localization enables effective participation in pH and bicarbonate regulation, which are vital for maintaining acid-base balance in the body. CA XIII shares highest homology with CA I, CA II, and CA III, suggesting potential overlapping functions and interactions within the carbonic anhydrase family. Sulfanilyl-sulfonamide type inhibitors have shown efficient inhibition of CA XIII activity, indicating potential therapeutic applications. Anti-CA XIII antibody (D-8) serves as an essential tool for researchers investigating carbonic anhydrases in health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    CA XIII Antibody (D-8)

    sc-374517
    200 µg/ml
    $316.00

    CA XIII Antibody (D-8): m-IgGλ BP-HRP Bundle

    sc-522765
    200 µg Ab, 40 µg BP
    $354.00

    CA XIII (D-8) Neutralizing Peptide

    sc-374517 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-374517 P appropriate for?

    Asked by: jerojero
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Robust signal in WB in HepG2 whole cell lysateRobust signal in WB in HepG2 whole cell lysate. -SCBT QC
    Date published: 2015-03-31
    Rated 5 out of 5 by from Great immunoperoxidase cytoplasmic and nuclearGreat immunoperoxidase cytoplasmic and nuclear staining in formalin fixed, paraffin-embedded human gall bladder tissue. -SCBT QC
    Date published: 2015-02-23
    Rated 5 out of 5 by from Positive signal in WB in Hs 181 Tes and WiDRPositive signal in WB in Hs 181 Tes and WiDR whole cell lysates. -SCBT QC
    Date published: 2015-01-27
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    CA XIII Antibody (D-8) is rated 5.0 out of 5 by 3.
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