CA VII Antibody (H-4): sc-166783

CA VII Antibody (H-4) is a mouse monoclonal IgG1 antibody that detects carbonic anhydrase VII (CA VII) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CA VII is a highly conserved member of the carbonic anhydrase family, which plays a crucial role in catalyzing the reversible hydration of carbon dioxide, a process vital for maintaining acid-base balance and facilitating various physiological functions. CA VII is predominantly located in the cytoplasm and is expressed at low levels across many tissues, with particularly high expression in the brain and salivary glands. CA VII′s presence in the brain is significant as CA VII may influence GABAergic excitation in neurons, potentially contributing to the pathophysiology of neurological disorders, including epilepsy and Alzheimer′s disease. CA VII′s ability to modulate neuronal excitability highlights CA VII′s importance as a target for pharmacological interventions aimed at managing these conditions. With diverse applications and critical role in brain function, anti-CA VII antibody (H-4) is an essential tool for researchers investigating the molecular mechanisms underlying neurological health and disease.

The preferred CA VII antibody is CA VII Antibody (G-7): sc-166721.