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CA-074 methyl ester is a cell-permeable analog of CA-074 (sc-202513) that acts as an irreversible cathepsin B inhibitor. CA-074 methyl ester is reported to inhibit bone reabsorption in rodent models and shown to inhibit B16 melanoma cell invasion in vitro.
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2. Montaser, M., et al. 2002. Biol. Chem. 383: 1305-1308. PMID: 12437121
See how others have used CA-074 methyl ester. Click on the entry to view the PubMed entry .
PMID: # 30387075 Prado Spalm, FH. et al. 2018. Mol. Neurobiol.
PMID: # 27840291 Tylichová, Z. et al. 2017. J. Nutr. Biochem. 39: 145-155.
PMID: # 26911557 Li, W. et al. 2016. BMC Vet. Res. 12: 36.
PMID: # 27729455 2016. J. Biol. Chem. 291: 24779-24786.
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