C8 Dihydroceramide (CAS 145774-33-0)

C8 Dihydroceramide is a chemically modified sphingolipid variant where the typical double bond in the sphingosine backbone is hydrogenated, resulting in a saturated structure. This modification imparts distinct biophysical properties to the molecule compared to its unsaturated counterpart, C8 Ceramide. In research, C8 Dihydroceramide is primarily used to explore the role of ceramides and their derivatives in cell membrane dynamics and signaling processes. The absence of the double bond affects the molecule′s interaction with cellular membranes, influencing membrane fluidity, domain formation, and the overall lipid environment. These changes are crucial for understanding how cells regulate signaling pathways involved in cell survival, proliferation, and apoptosis under various physiological conditions. Moreover, C8 Dihydroceramide serves as a critical tool in the study of sphingolipid metabolism, helping explain the enzymatic pathways involved in the conversion of dihydroceramides to ceramides and other complex sphingolipids. Researchers utilize this compound to dissect the specific roles of different ceramide species in cellular mechanisms, providing insights into the lipid-mediated regulation of cell function and the impact of lipid saturation on these processes. Through such studies, C8 Dihydroceramide contributes to a broader understanding of lipid biochemistry and its implications in cellular health and adaptability.