C6 Whole Cell Lysate: sc-364373

The C6 Whole Cell Lysate is derived from the C6 cell line, a well-established model that originates from rat glial cells, specifically glioma cells. This lysate is a comprehensive mixture of intracellular components including proteins, nucleic acids, lipids, and metabolites, extracted through methods such as chemical lysis, sonication, or enzymatic disruption to ensure a wide representation of cellular material. Widely used in non-medical research, C6 Whole Cell Lysate enables scientists to delve into the basic understanding of glial cell functions and the cellular mechanisms underlying cell communication and response to external stimuli. It plays a crucial role in neuroscience research, offering insights into the cellular architecture and biochemical pathways of glial cells. Researchers utilize this lysate in various applications such as the study of protein-protein interactions, the validation of biochemical assays, and the examination of cellular responses in experimental setups that mimic physiological conditions. Additionally, the C6 Whole Cell Lysate serves as a reference material in comparative studies, helping to identify changes in protein expression or signaling pathways under different experimental conditions. Its use has been instrumental in advancing our fundamental knowledge of cell biology, particularly in understanding the roles of glial cells in various cellular processes.

C6 Whole Cell Lysate References:

1. αvβ5 integrin mediates the effect of vitronectin on the initial stage of differentiation in mouse cerebellar granule cell precursors.  |  Abe, A., et al. 2018. Brain Res. 1691: 94-104. PMID: 29702083
2. Heterogeneous expression of transketolase in rat brain.  |  Calingasan, NY., et al. 1995. J Neurochem. 64: 1034-44. PMID: 7861132