Molecular structure of C6 Dihydroceramide, CAS Number: 171039-13-7
C6 Dihydroceramide (CAS 171039-13-7)
Application:
C6 Dihydroceramide is a negative control for C6 Ceramide
CAS Number:
171039-13-7
Purity:
98%
Molecular Weight:
399.65
Molecular Formula:
C24H49NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
C6 Dihydroceramide is used as a negative control for C6 Ceramide. C6 Dihydroceramide serves as a signaling molecule employed by bacteria to govern the expression of genes. This multifaceted compound plays a significant role in various bacterial processes, encompassing quorum sensing (QS), biofilm formation, and virulence. Its intricate structure comprises an acyl chain, a lactone ring, and an amide group. Scientists utilize C6 Dihydroceramide to investigate the intricate mechanisms underlying gene expression regulation in bacteria, as well as to unravel its impact on biofilm formation and virulence.
C6 Dihydroceramide (CAS 171039-13-7) References
- Acceleration by ceramide of calcium-dependent translocation of phospholipase A2 from cytosol to membranes in platelets. | Kitatani, K., et al. 2000. Arch Biochem Biophys. 382: 296-302. PMID: 11068881
- Regulation of cyclin-dependent kinase 2 activity by ceramide. | Lee, JY., et al. 2000. Exp Cell Res. 261: 303-11. PMID: 11112337
- Ceramide inhibits L-type calcium channel currents in GH3 cells. | Chik, CL., et al. 2004. Mol Cell Endocrinol. 218: 175-83. PMID: 15130522
- Ydc1p ceramidase triggers organelle fragmentation, apoptosis and accelerated ageing in yeast. | Aerts, AM., et al. 2008. Cell Mol Life Sci. 65: 1933-42. PMID: 18500447
- Neutral sphingomyelinase 2: a novel target in cigarette smoke-induced apoptosis and lung injury. | Filosto, S., et al. 2011. Am J Respir Cell Mol Biol. 44: 350-60. PMID: 20448054
- Mitochondrial dysfunction links ceramide activated HRK expression and cell death. | Rizvi, F., et al. 2011. PLoS One. 6: e18137. PMID: 21483866
- The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation. | Fonseca, BM., et al. 2013. Apoptosis. 18: 1526-35. PMID: 24048885
- Phosphoglycerol dihydroceramide, a distinctive ceramide produced by Porphyromonas gingivalis, promotes RANKL-induced osteoclastogenesis by acting on non-muscle myosin II-A (Myh9), an osteoclast cell fusion regulatory factor. | Kanzaki, H., et al. 2017. Biochim Biophys Acta Mol Cell Biol Lipids. 1862: 452-462. PMID: 28153611
- Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide. | Bielawska, A., et al. 1993. J Biol Chem. 268: 26226-32. PMID: 8253743
- Inhibition of the expression of ornithine decarboxylase and c-Myc by cell-permeant ceramide in difluoromethylornithine-resistant leukaemia cells. | Flamigni, F., et al. 1997. Biochem J. 324 (Pt 3): 783-9. PMID: 9210401
- Synovial fibroblasts and the sphingomyelinase pathway: sphingomyelin turnover and ceramide generation are not signaling mechanisms for the actions of tumor necrosis factor-alpha. | Gerritsen, ME., et al. 1998. Am J Pathol. 152: 505-12. PMID: 9466577
- Bipotential roles of ceramide in the growth of hippocampal neurons: promotion of cell survival and dendritic outgrowth in dose- and developmental stage-dependent manners. | Mitoma, J., et al. 1998. J Neurosci Res. 51: 712-22. PMID: 9545085
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
C6 Dihydroceramide, 5 mg | sc-210994 | 5 mg | $91.00 |