C22 Dihydroceramide (CAS 147492-65-7)

C22 Dihydroceramide, with the CAS number 147492-65-7, is a bioactive lipid molecule that belongs to the class of ceramides, characterized by a sphingosine backbone linked to a fatty acid via an amide bond, with the fatty acid in this instance being a 22-carbon chain. Unlike typical ceramides, dihydroceramides lack the double bond in the sphingosine base, which results in differing physical properties and biological interactions. This structural feature makes C22 dihydroceramide particularly interesting for research in cell biology and biochemistry, where it is often used to study lipid metabolism pathways and the role of lipids in cellular signaling mechanisms. The absence of a double bond increases its stability, making it a useful tool in studies of oxidative stress and longevity, as dihydroceramides are less susceptible to oxidation than ceramides. In research, C22 dihydroceramide is utilized to explore the fundamental processes involving ceramide metabolism, such as the role of ceramides in the formation of lipid rafts, cellular apoptosis, and the regulation of other signaling pathways within cells. Additionally, this compound aids in the investigation of the sphingolipid rheostat, which balances the levels of ceramides and sphingosine-1-phosphate, crucial for understanding cell fate decisions in various physiological and pathophysiological contexts.