C2 Ceramide-1-phosphate (CAS 151729-55-4)

C2 Ceramide-1-phosphate, with the CAS number 151729-55-4, is a synthetic analog of naturally occurring ceramide-1-phosphate, distinguished by its C2 acyl chain length. This compound is a pivotal sphingolipid that plays a role in various cellular processes, primarily through its involvement in signaling pathways rather than direct participation in structural components of cell membranes. The structure of C2 Ceramide-1-phosphate includes a sphingosine backbone linked to a fatty acid by an amide bond, with a phosphate group esterified to the hydroxyl group of sphingosine. This configuration confers unique biophysical properties to the molecule, including the ability to interact with specific proteins that mediate intracellular signaling. In research contexts, this compound has been extensively used to study the mechanisms by which ceramide-1-phosphate influences cellular behavior, particularly focusing on its role in modulating cell survival, proliferation, and apoptosis in non-medical experimental setups. Researchers have also explored its effects on cellular stress responses and its potential as a bioactive molecule in signal transduction studies. Moreover, C2 Ceramide-1-phosphate has been instrumental in the investigation of lipid rafts and their dynamics within cellular membranes, providing insights into how lipid composition and localization affect cellular function and signaling pathways. These studies contribute significantly to the broader understanding of lipid-mediated cellular processes, enhancing our knowledge of cell biology and biochemistry in fundamental research.