C. trachomatis Antibody (Clone 3): sc-73569
- C. trachomatis Antibody (Clone 3) is a mouse monoclonal IgG3 provided at 500 µl supernatant
- raised against purified LPS of C. trachomatis origin
- recommended for detection of serotypes A, B, Ba, C, D, E, F, G, H, I, J, K, L2 and L3 of Chlamydia trachomatis origin by IF and IHC(P)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for C. trachomatis Antibody (Clone 3). This work is in progress.
QUICK LINKS
C. trachomatis Antibody (Clone 3) is a mouse monoclonal IgG3 antibody that detects Chlamydia trachomatis across various serotypes including A, B, Ba, C, D, E, F, G, H, I, J, K, L2, and L3, by immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). C. trachomatis (Clone 3) antibody is available in a non-conjugated form, allowing for flexible experimental design. Chlamydia trachomatis is an intracellular bacterium that plays a significant role in human health, being responsible for several major diseases, including endemic trachoma and sexually transmitted infections. The protein structure of Chlamydia trachomatis features a major outer membrane protein (MOMP) that is crucial for the bacterium′s ability to evade the host immune response. MOMP forms a protective barrier, allowing the bacterium to survive and replicate within host cells, which is essential for pathogenicity. Specific epitopes within the variable region 4 (VS4) of MOMP are recognized by monoclonal antibodies, making these antibodies valuable tools for diagnosing infections and understanding the immune response to Chlamydia trachomatis. Detection of Chlamydia trachomatis using C. trachomatis (Clone 3) monoclonal antibody is vital for both clinical diagnostics and research applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
C. trachomatis Antibody (Clone 3) References:
- Direct detection and magnetic isolation of Chlamydia trachomatis major outer membrane protein-specific CD8+ CTLs with HLA class I tetramers. | Kim, SK., et al. 2000. J Immunol. 165: 7285-92. PMID: 11120863
- Importance of species-specific antigens in the serodiagnosis of Chlamydia trachomatis reactive arthritis. | Bas, S., et al. 2002. Rheumatology (Oxford). 41: 1017-20. PMID: 12209035
- Antibodies to Chlamydia trachomatis heat shock protein 60 (cHSP60) and Chlamydia trachomatis major outer membrane protein (MOMP) in women with different tubal status. | Clad, A., et al. 2003. Clin Lab. 49: 269-71. PMID: 15285186
- Characterization of the disulfide bonds and free cysteine residues of the Chlamydia trachomatis mouse pneumonitis major outer membrane protein. | Yen, TY., et al. 2005. Biochemistry. 44: 6250-6. PMID: 15835913
- Chlamydia trachomatis enters a viable but non-cultivable (persistent) state within herpes simplex virus type 2 (HSV-2) co-infected host cells. | Deka, S., et al. 2006. Cell Microbiol. 8: 149-62. PMID: 16367874
- Development and validation of a rotor-gene real-time PCR assay for detection, identification, and quantification of Chlamydia trachomatis in a single reaction. | Jalal, H., et al. 2006. J Clin Microbiol. 44: 206-13. PMID: 16390971
- Deoxyribonucleic Acid Heterogeneity Between Human and Murine Strains of Chlamydia trachomatis. | Weiss, E., et al. 1970. Infect Immun. 2: 24-8. PMID: 16557794
- Studies on the developmental cycle of Chlamydia trachomatis: isolation and characterization of the initial bodies. | Gutter, B., et al. 1973. J Bacteriol. 115: 691-702. PMID: 4125248
- Characterization of the group antigen of Chlamydia trachomatis. | Dhir, SP., et al. 1971. Infect Immun. 4: 725-30. PMID: 5154904
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
C. trachomatis Antibody (Clone 3) | sc-73569 | 500 µl supernatant | $322.00 |