Molecular structure of c-Src substrate
c-Src substrate Substrate
Alternate Names:
Src substrate II; H-Tyr-Ile-Tyr-Gly-Ser-Phe-Lys-OH
Application:
c-Src substrate is a synthetic substrate for c-Src
Purity:
>97% pure by HPLC
Molecular Weight:
877.3
Molecular Formula:
C44H60N8O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
c-Src substrate is a synthetic substrate for c-Src. It is a specific and efficient substrate for the src family tyrosine kinases.
c-Src substrate Substrate References
- Inhibition of platelet integrin alpha(IIb)beta(3) by peptides that interfere with protein kinases and the beta(3) tail. | Hers, I., et al. 2000. Arterioscler Thromb Vasc Biol. 20: 1651-60. PMID: 10845885
- Antibody-based fluorescence detection of kinase activity on a peptide array. | Lesaicherre, ML., et al. 2002. Bioorg Med Chem Lett. 12: 2085-8. PMID: 12127509
- Applications of one-bead one-compound combinatorial libraries and chemical microarrays in signal transduction research. | Lam, KS., et al. 2003. Acc Chem Res. 36: 370-7. PMID: 12809522
- Development and characterization of potent and specific peptide inhibitors of p60c-src protein tyrosine kinase using pseudosubstrate-based inhibitor design approach. | Kamath, JR., et al. 2003. J Pept Res. 62: 260-8. PMID: 14632929
- Entrapment of Src protein tyrosine kinase in sugar-modified silica. | Cruz-Aguado, JA., et al. 2004. Anal Chem. 76: 4182-8. PMID: 15253661
- Synthesis and structure-activity relationships of linear and conformationally constrained peptide analogues of CIYKYY as Src tyrosine kinase inhibitors. | Kumar, A., et al. 2006. J Med Chem. 49: 3395-401. PMID: 16722659
- Synthesis and evaluation of 3-phenylpyrazolo[3,4-d]pyrimidine-peptide conjugates as Src kinase inhibitors. | Kumar, A., et al. 2007. ChemMedChem. 2: 1346-60. PMID: 17530729
- What is the structure of b(2) ions generated from doubly protonated tryptic peptides? | Bythell, BJ., et al. 2009. J Am Soc Mass Spectrom. 20: 618-24. PMID: 19109036
- Automated maskless photolithography system for peptide microarray synthesis on a chip. | Shin, DS., et al. 2010. J Comb Chem. 12: 463-71. PMID: 20666398
- Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. | Guo, W., et al. 2012. Mol Pharmacol. 82: 938-47. PMID: 22899868
- Purification of a Src family tyrosine protein kinase from bovine retinas. | Perdomo, D. and Bubis, J. 2021. Z Naturforsch C J Biosci. 76: 273-283. PMID: 33125342
- Identification and characterization of a novel synthetic peptide substrate specific for Src-family protein tyrosine kinases. | Lam, KS., et al. 1995. Int J Pept Protein Res. 45: 587-92. PMID: 7558590
- Identifying substrate motifs of protein kinases by a random library approach. | Wu, J., et al. 1994. Biochemistry. 33: 14825-33. PMID: 7993909
- Identification of GIYWHHY as a novel peptide substrate for human p60c-src protein tyrosine kinase. | Lou, Q., et al. 1996. Bioorg Med Chem. 4: 677-82. PMID: 8804533
- Discovery of a novel series of potent and selective substrate-based inhibitors of p60c-src protein tyrosine kinase: conformational and topographical constraints in peptide design. | Alfaro-Lopez, J., et al. 1998. J Med Chem. 41: 2252-60. PMID: 9632358
Substrate of:
SRC.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
c-Src substrate, 2 mg | sc-3116 | 2 mg | $96.00 |