Molecular structure of c-Met/RON Dual Kinase Inhibitor, CAS Number: 913376-84-8
c-Met/RON Dual Kinase Inhibitor (CAS 913376-84-8)
Alternate Names:
Met Kinase Inhbitor IV; Ron Inhibitor I
Application:
c-Met/RON Dual Kinase Inhibitor is an inhibitor of both Met and Ron
CAS Number:
913376-84-8
Purity:
≥95%
Molecular Weight:
556.58
Molecular Formula:
C31H29FN4O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Met/Ron Dual Kinase Inhibitor is an inhibitor of both Met and Ron.
c-Met/RON Dual Kinase Inhibitor (CAS 913376-84-8) References
- Identification of a novel recepteur d'origine nantais/c-met small-molecule kinase inhibitor with antitumor activity in vivo. | Zhang, Y., et al. 2008. Cancer Res. 68: 6680-7. PMID: 18701492
- IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk. | Tian, Y., et al. 2014. Mol Cell Biol. 34: 3546-58. PMID: 25022754
- Hepatocyte growth factor triggers distinct mechanisms of Asef and Tiam1 activation to induce endothelial barrier enhancement. | Higginbotham, K., et al. 2014. Cell Signal. 26: 2306-16. PMID: 25101856
- Microtubule dynamics control HGF-induced lung endothelial barrier enhancement. | Tian, X., et al. 2014. PLoS One. 9: e105912. PMID: 25198505
- Hepatocyte growth factor-induced Asef-IQGAP1 complex controls cytoskeletal remodeling and endothelial barrier. | Tian, Y., et al. 2015. J Biol Chem. 290: 4097-109. PMID: 25492863
- Asef controls vascular endothelial permeability and barrier recovery in the lung. | Tian, X., et al. 2015. Mol Biol Cell. 26: 636-50. PMID: 25518936
- Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction. | Meng, F., et al. 2015. Am J Physiol Lung Cell Mol Physiol. 308: L452-63. PMID: 25539852
Inhibitor of:
Met, and Ron.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
c-Met/RON Dual Kinase Inhibitor, 5 mg | sc-364532 | 5 mg | $379.00 | |||
c-Met/RON Dual Kinase Inhibitor, 50 mg | sc-364532A | 50 mg | $1200.00 | |||
c-Met/RON Dual Kinase Inhibitor, 100 mg | sc-364532B | 100 mg | $1700.00 | |||
c-Met/RON Dual Kinase Inhibitor, 500 mg | sc-364532C | 500 mg | $3600.00 | |||
c-Met/RON Dual Kinase Inhibitor, 1 g | sc-364532D | 1 g | $7000.00 |