C. abortus LPS Antibody (13/4): sc-101593

C. abortus LPS Antibody (13/4) is a mouse monoclonal IgG1 kappa light chain antibody that detects C. abortus LPS protein of C. abortus origin by western blotting (WB), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). C. abortus LPS (13/4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Chlamydophila abortus, also known as Chlamydia psittaci, is a gram-negative intracellular bacterium that primarily colonizes the placenta of animals, leading to abortion during the late stages of gestation. This pathogen is significant not only as an enzootic agent affecting livestock but also as a zoonotic threat to humans. C. abortus LPS plays a crucial role in the bacterium′s virulence, as this key component of the outer membrane helps the organism evade the host′s immune response. The lipopolysaccharide (LPS) structure is essential for maintaining the integrity of the bacterial cell wall and is involved in the interaction with host cells, influencing the inflammatory response. The unique composition of C. abortus, which includes transmembrane helical proteins and polymorphic membrane proteins, contributes to its pathogenicity and host specificity. Understanding C. abortus LPS function is vital for developing effective diagnostic tools and therapeutic strategies against infections caused by this organism.

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C. abortus LPS Antibody (13/4) References:

1. Chlamydial infection in sheep: immune control versus fetal pathology.  |  Entrican, G., et al. 2001. J R Soc Med. 94: 273-7. PMID: 11387415
2. Polymorphic outer-membrane proteins of Chlamydophila abortus are glycosylated.  |  Vretou, E., et al. 2001. Microbiology (Reading). 147: 3303-10. PMID: 11739762
3. Expression of the major outer membrane protein (MOMP) of Chlamydophila abortus, Chlamydophila pecorum, and Chlamydia suis in Escherichia coli using an arabinose-inducible plasmid vector.  |  Hoelzle, LE., et al. 2003. J Vet Med B Infect Dis Vet Public Health. 50: 383-9. PMID: 14633208
4. The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation.  |  Thomson, NR., et al. 2005. Genome Res. 15: 629-40. PMID: 15837807
5. Role of polymorphonuclear neutrophils (PMNs) and NK cells in the protection conferred by different vaccines against Chlamydophila abortus infection.  |  Ortega, N., et al. 2007. Res Vet Sci. 82: 314-22. PMID: 17046037
6. Therapeutic Chlamydophila abortus and C. pecorum vaccination transiently reduces bovine mastitis associated with Chlamydophila infection.  |  Biesenkamp-Uhe, C., et al. 2007. Infect Immun. 75: 870-7. PMID: 17118976
7. Epidemiological and pathological study on the causes of abortion in sheep and goats in Hungary (1998-2005).  |  Szeredi, L., et al. 2006. Acta Vet Hung. 54: 503-15. PMID: 17278722
8. Evaluation of two commercial assays for the detection of Chlamydophila abortus antibodies.  |  Vretou, E., et al. 2007. Vet Microbiol. 123: 153-61. PMID: 17382493
9. Infectious disease monitoring of the endangered Hawaiian monk seal.  |  Aguirre, AA., et al. 2007. J Wildl Dis. 43: 229-41. PMID: 17495307

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-C. abortus LPS Antibody (13/4) has 7 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

C. abortus LPS Antibody (13/4) Specifications

Alternate Product Name: C. abortus LPS

Product Clone Name: 13/4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: C. abortus LPS

Epitope Species: C. abortus

Product Reactivity/Detection: LPS from all species

Species Reactivity/Detection: C. abortus

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 7 citations in various scientific publications

Available Conjugates/Forms for C. abortus LPS Antibody (13/4): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin