Molecular structure of C-6 NBD-dihydro-Ceramide, CAS Number: 114301-95-0
C-6 NBD-dihydro-Ceramide (CAS 114301-95-0)
Alternate Names:
N-C6-NBD-D-erythro-dihydro-Sphingosine
Application:
C-6 NBD-dihydro-Ceramide is a biologically active fluorescent probe
CAS Number:
114301-95-0
Molecular Weight:
577.8
Molecular Formula:
C30H51N5O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
C-6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-permeable ceramides. It is as effective as C-6 ceramide in the inhibition of viral glycoprotein transport through the Golgi.1 C-6 NBD ceramide has been used as a fluorescent substrate for the activity of UDP-glucose:ceramide glucosyltransferase2 and to demonstrate the translocation of glucocerebroside and sphingomyelin from the Golgi to the plasma membrane.3 C-6 NBD-dihydro-Ceramide is structurally indistinguishable to C-6 NBD ceramide, except it contains a saturated bond in the C-4/C-5 position of the sphingosine backbone.
C-6 NBD-dihydro-Ceramide (CAS 114301-95-0) References
1 Rosenwald, A.G., Pagano, R.E. Inhibition of glycoprotein traffic through the secretory pathway by ceramide. J. Biol. Chem. 268 4577-4579 (1993). 2 Paul, P., Kamisaka, Y., Marks, D.L., et al. Purification and characterization of UDP-glucose: Ceramide glucosyltransferase from rat liver Golgi membranes. J Biol Chem 271 2287-2293 (1996). 3 Lipsky, N.G., Pagano, R.E. Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: Endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the golgi apparatus en route to the plasma membrane. J Cell Biol 100 27-34 (1985).Substrate of:
Fluorogenic.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
C-6 NBD-dihydro-Ceramide, 1 mg | sc-204662 | 1 mg | $255.00 | |||
C-6 NBD-dihydro-Ceramide, 5 mg | sc-204662A | 5 mg | $1040.00 |