Date published: 2026-5-22

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BYK 191023 dihydrochloride (CAS 608880-48-4)

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Application:
BYK 191023 dihydrochloride is a selective inhibitor of NOS2
CAS Number:
608880-48-4
Molecular Weight:
327.21
Molecular Formula:
C14H14N4O•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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BYK 191023 dihydrochloride is utilized in biochemical research, particularly in studies related to enzyme inhibition. It serves as an inhibitor for a variety of enzymes, which is instrumental in understanding enzyme mechanisms and function. Researchers use BYK 191023 dihydrochloride to investigate the biochemical pathways that are regulated by these enzymes, providing insights into how they influence cellular processes. Additionally, this compound is used in the study of signal transduction pathways, offering a tool to dissect the complex signaling mechanisms within cells. The ability of BYK 191023 dihydrochloride to modulate enzyme activity makes it a valuable agent in exploratory biochemistry research aimed at elucidating the roles of specific enzymes within biological systems.


BYK 191023 dihydrochloride (CAS 608880-48-4) References

  1. The novel imidazopyridine 2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) is a highly selective inhibitor of the inducible nitric-oxide synthase.  |  Strub, A., et al. 2006. Mol Pharmacol. 69: 328-37. PMID: 16223957
  2. In vivo characterization of the novel imidazopyridine BYK191023 [2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a potent and highly selective inhibitor of inducible nitric-oxide synthase.  |  Lehner, MD., et al. 2006. J Pharmacol Exp Ther. 317: 181-7. PMID: 16368897
  3. BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase.  |  Tiso, M., et al. 2008. Mol Pharmacol. 73: 1244-53. PMID: 18178668
  4. iNOS-selective inhibitors for cancer prevention: promise and progress.  |  Janakiram, NB. and Rao, CV. 2012. Future Med Chem. 4: 2193-204. PMID: 23190107
  5. Transdifferentiation Requires iNOS Activation: Role of RING1A S-Nitrosylation.  |  Meng, S., et al. 2016. Circ Res. 119: e129-e138. PMID: 27623813

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

BYK 191023 dihydrochloride, 10 mg

sc-361131
10 mg
$161.00

BYK 191023 dihydrochloride, 50 mg

sc-361131A
50 mg
$686.00