Date published: 2026-6-8

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BW373U86 dihydrobromide

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Molecular Weight:
597.43
Molecular Formula:
C27H37N3O22HBr
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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BW373U86 dihydrobromide is a potent non-peptide agonist for δ-opioid receptor.


BW373U86 dihydrobromide References

  1. BW373U86, a delta opioid agonist, partially mediates delayed cardioprotection via a free radical mechanism that is independent of opioid receptor stimulation.  |  Patel, HH., et al. 2001. J Mol Cell Cardiol. 33: 1455-65. PMID: 11448134
  2. Comparison of receptor mechanisms and efficacy requirements for delta-agonist-induced convulsive activity and antinociception in mice.  |  Broom, DC., et al. 2002. J Pharmacol Exp Ther. 303: 723-9. PMID: 12388657
  3. Delta opioid receptor agonist BW373U86 attenuates post-resuscitation brain injury in a rat model of asphyxial cardiac arrest.  |  Yang, L., et al. 2014. Resuscitation. 85: 299-305. PMID: 24200890
  4. BW373U86 upregulates autophagy by inhibiting the PI3K/Akt pathway and regulating the mTOR pathway to protect cardiomyocytes from hypoxia-reoxygenation injury.  |  Liang, Q., et al. 2020. Can J Physiol Pharmacol. 98: 684-690. PMID: 32955950
  5. BW373U86, a delta-opioid receptor agonist, reverses bradykinin-induced thermal allodynia in rhesus monkeys.  |  Butelman, ER., et al. 1995. Eur J Pharmacol. 277: 285-7. PMID: 7493622
  6. Behavioral effects of the systemically active delta opioid agonist BW373U86 in rhesus monkeys.  |  Negus, SS., et al. 1994. J Pharmacol Exp Ther. 270: 1025-34. PMID: 7932149
  7. BW373U86: a nonpeptidic delta-opioid agonist with novel receptor-G protein-mediated actions in rat brain membranes and neuroblastoma cells.  |  Childers, SR., et al. 1993. Mol Pharmacol. 44: 827-34. PMID: 8232233
  8. Discriminative stimulus effects of BW373U86: a nonpeptide ligand with selectivity for delta opioid receptors.  |  Comer, SD., et al. 1993. J Pharmacol Exp Ther. 267: 866-74. PMID: 8246161
  9. A novel delta opioid agonist, BW373U86, in squirrel monkeys responding under a schedule of shock titration.  |  Dykstra, LA., et al. 1993. J Pharmacol Exp Ther. 267: 875-82. PMID: 8246162
  10. A nonpeptidic delta opioid receptor agonist, BW373U86, attenuates the development and expression of morphine abstinence precipitated by naloxone in rat.  |  Lee, PH., et al. 1993. J Pharmacol Exp Ther. 267: 883-7. PMID: 8246163
  11. Alkaloid delta agonist BW373U86 increases hypoxic tolerance.  |  Bofetiado, DM., et al. 1996. Anesth Analg. 82: 1237-41. PMID: 8638797
  12. Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors.  |  Knapp, RJ., et al. 1996. J Pharmacol Exp Ther. 277: 1284-91. PMID: 8667189
  13. Antagonistic modulation between the delta opioid agonist BW373U86 and the mu opioid agonist fentanyl in mice.  |  O'Neill, SJ., et al. 1997. J Pharmacol Exp Ther. 282: 271-7. PMID: 9223564
  14. Renal excretory responses produced by the delta opioid agonist, BW373U86, in conscious rats.  |  Sezen, SF., et al. 1998. J Pharmacol Exp Ther. 287: 238-45. PMID: 9765343
  15. Dopamine-dependent behavioural stimulation by non-peptide delta opioids BW373U86 and SNC 80: 2. Place-preference and brain microdialysis studies in rats.  |  Longoni, R., et al. 1998. Behav Pharmacol. 9: 9-14. PMID: 9832943

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

BW373U86 dihydrobromide, 10 mg

sc-300314
10 mg
$865.00