Molecular structure of Butyrylcholine chloride, CAS Number: 2963-78-2
Butyrylcholine chloride (CAS 2963-78-2)
Alternate Names:
2-butanoyloxyethyl(trimethyl)azanium chloride
Application:
Butyrylcholine chloride is a substrate of BChE and AChE
CAS Number:
2963-78-2
Purity:
≥98%
Molecular Weight:
209.71
Molecular Formula:
C9H20NO2Cl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Butyrylcholine chloride, referred to as BCh, is an organic compound. It is an ester of butyric acid and choline, and functions as a quaternary ammonium salt. In terms of its mechanism of action, Butyrylcholine chloride acts as an agonist for the muscarinic acetylcholine receptors. By binding to these receptors, it triggers their activation. Butyrylcholine chloride binds to multiple muscarinic receptor subtypes, including M1, M2, M3, M4, and M5. Activation of the M1 and M2 receptors initiates the release of neurotransmitters, such as acetylcholine, which subsequently activate other receptors. Activation of the M3, M4, and M5 receptors prompts the release of hormones, including epinephrine and norepinephrine.
Butyrylcholine chloride (CAS 2963-78-2) References
- A novel enzyme biosensor for steroidal glycoalkaloids detection based on pH-sensitive field effect transistors. | Korpan, YI., et al. 2002. Bioelectrochemistry. 55: 9-11. PMID: 11786329
- Application of a cholinesterase biosensor to screen for organophosphorus pesticides extracted from soil. | Kumaran, S. and Morita, M. 1995. Talanta. 42: 649-55. PMID: 18966276
- Enzyme-octadecylamine Langmuir-Blodgett membranes for ENFET biosensors. | Wan, K., et al. 2000. Talanta. 52: 663-70. PMID: 18968024
- The use of polyethyleneimine for fabrication of potentiometric cholinesterase biosensors. | Reybier, K., et al. 2002. Talanta. 56: 1015-20. PMID: 18968581
- Cholinesterases inhibitory and antioxidant activities of Harpagophytum procumbens from in vitro systems. | Georgiev, MI., et al. 2012. Phytother Res. 26: 313-6. PMID: 21721061
- Determination of serum cholinesterase activity and dibucaine numbers by an amperometric choline sensor. | Palleschi, G., et al. 1990. Biosens Bioelectron. 5: 27-35. PMID: 2178637
- Quantum dots-based fluorescent probes for turn-on and turn-off sensing of butyrylcholinesterase. | Chen, Z., et al. 2013. Biosens Bioelectron. 44: 204-9. PMID: 23428734
- Urease-based ISFET biosensor for arginine determination. | Sheliakina, M., et al. 2014. Talanta. 121: 18-23. PMID: 24607104
- Quinoxaline derivatives: novel and selective butyrylcholinesterase inhibitors. | Zeb, A., et al. 2014. Med Chem. 10: 724-9. PMID: 24875826
- Engineering Systems with Spatially Separated Enzymes via Dual-Stimuli-Sensitive Properties of Microgels. | Sigolaeva, LV., et al. 2015. Langmuir. 31: 13029-39. PMID: 26539639
- In-vitro evaluation and in-silico studies applied on newly synthesized amide derivatives of N-phthaloylglycine as Butyrylcholinesterase (BChE) inhibitors. | Begum, S., et al. 2018. Comput Biol Chem. 74: 212-217. PMID: 29653432
- Ultrasensitive detection of butyrylcholinesterase activity based on the inner filter effect of MnO2 nanosheets on sulfur nanodots. | Li, T., et al. 2020. Analyst. 145: 5206-5212. PMID: 32578586
- Investigation of characteristics of urea and butyrylcholine chloride biosensors based on ion-selective field-effect transistors modified by the incorporation of heat-treated zeolite Beta crystals. | Soy, E., et al. 2012. Mater Sci Eng C Mater Biol Appl. 32: 1835-1842. PMID: 34062664
- Phytochemical Profiling, Antioxidant, Antimicrobial and Cholinesterase Inhibitory Effects of Essential Oils Isolated from the Leaves of Artemisia scoparia and Artemisia absinthium. | Khan, FA., et al. 2022. Pharmaceuticals (Basel). 15: PMID: 36297333
- Effects of activin A/erythroid differentiation factor on erythroid and megakaryocytic differentiations of mouse erythroleukemia (Friend) cells: evidence for two distinct modes of cell response. | Okafuji, K., et al. 1995. Exp Hematol. 23: 210-6. PMID: 7875239
Substrate of:
AChE, and BChE.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Butyrylcholine chloride, 10 g | sc-255007 | 10 g | $55.00 | |||
Butyrylcholine chloride, 25 g | sc-255007A | 25 g | $141.00 |