Date published: 2026-5-7

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Butyrolactone II (CAS 87414-44-6)

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Application:
Butyrolactone II is an antibiotic, a 5-LOX inhibitor and has shown DPPH radical-scavening activity
CAS Number:
87414-44-6
Molecular Weight:
356.33
Molecular Formula:
C19H16O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Butyrolactone II is a chemical compound that belongs to the class of lactones, which are cyclic esters of hydroxy acids. It features a four-membered lactone ring, a structure that imparts distinctive chemical properties including reactivity and stability. This compound has been a subject of interest primarily in the field of organic chemistry and materials science. In research contexts, Butyrolactone II has been utilized extensively to study ring-opening polymerization processes. These studies focus on understanding how the lactone ring can be cleaved under certain conditions to form polymers with specific properties. Researchers investigate various catalysts and conditions that can initiate and control this polymerization process, aiming to produce materials with desirable thermal and mechanical characteristics. Additionally, Butyrolactone II serves as a model compound in synthetic chemistry for exploring various organic reactions, such as esterification and transesterification, which are fundamental to developing synthetic pathways for more complex molecules. These reactions are crucial for constructing molecular architectures in a controlled and predictable manner.


Butyrolactone II (CAS 87414-44-6) References

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  2. Soybean lipoxygenase inhibitory and DPPH radical-scavenging activities of aspernolide A and butyrolactones I and II.  |  Sugiyama, Y., et al. 2010. Biosci Biotechnol Biochem. 74: 881-3. PMID: 20378968
  3. Application of an efficient gene targeting system linking secondary metabolites to their biosynthetic genes in Aspergillus terreus.  |  Guo, CJ., et al. 2013. Org Lett. 15: 3562-5. PMID: 23841722
  4. Territrem and butyrolactone derivatives from a marine-derived fungus Aspergillus terreus.  |  Nong, XH., et al. 2014. Mar Drugs. 12: 6113-24. PMID: 25522319
  5. Bioactive secondary metabolites from the marine-associated fungus Aspergillus terreus.  |  Liu, M., et al. 2018. Bioorg Chem. 80: 525-530. PMID: 30014920
  6. Metabolites from the Marine-Facultative Aspergillus sp. MEXU 27854 and Gymnoascus hyalinosporus MEXU 29901 from Caleta Bay, Mexico.  |  Aparicio-Cuevas, MA., et al. 2019. Tetrahedron Lett. 60: 1649-1652. PMID: 32390667
  7. Chemical Investigation of Marine-Derived Fungus Aspergillus flavipes for Potential Anti-Inflammatory Agents.  |  Tilvi, S., et al. 2021. Chem Biodivers. 18: e2000956. PMID: 33533162
  8. Bioactive aromatic butenolides from a mangrove sediment originated fungal species, Aspergillus terreus SCAU011.  |  Bao, J., et al. 2021. Fitoterapia. 150: 104856. PMID: 33582267
  9. Unveiling the Antimicrobial and Larvicidal Potential of Butyrolactones and Orsellinic Acid Derivatives from the Morus alba-derived Fungus Aspergillus terreus via Integrated In vitro and In silico Approaches.  |  Amr, K., et al. 2024. Chem Biodivers. 21: e202301900. PMID: 38282171
  10. Metabolic products of Aspergillus terreus. IX. Biosynthesis of butyrolactone derivatives isolated from strains IFO 8835 and 4100.  |  NITTA, KEIICHI, et al. 1983. Chemical and pharmaceutical bulletin. 31.5: 1528-1533.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Butyrolactone II, 500 µg

sc-396570
500 µg
$203.00