Date published: 2026-4-5

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Butylboronic acid (CAS 4426-47-5)

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Alternate Names:
n-Butylboronic acid
Application:
Butylboronic acid is a precursor to unsymmetric borinic acids, which are inhibitors of serine proteases.
CAS Number:
4426-47-5
Purity:
98%
Molecular Weight:
101.94
Molecular Formula:
C4H11BO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Butylboronic acid is a precursor to unsymmetric borinic acids, which are inhibitors of serine proteases. Can be used as a transport carrier in membrane-based sugar separations and as an analytical reagent in the determination of serum glucose. Butylboronic acid, a derivative of boronic acid, finds application in the synthesis of polymers, including polyurethanes and polyesters. Its catalytic properties make it invaluable as a catalyst in organic reactions, such as the Heck reaction and the Suzuki reaction. It plays a role in peptide synthesis, enabling the production of peptide hormones with specific biological activities. Additionally, in carbohydrate synthesis, butylboronic acid serves as a building block, allowing for the creation of glycosides and glycoproteins.


Butylboronic acid (CAS 4426-47-5) References

  1. Duvatrienediols in cuticular wax of Burley tobacco leaves.  |  Chang, SY. and Grunwald, C. 1976. J Lipid Res. 17: 7-11. PMID: 1255021
  2. Boric acid and boronic acids inhibition of pigeonpea urease.  |  Reddy, KR. and Kayastha, AM. 2006. J Enzyme Inhib Med Chem. 21: 467-70. PMID: 17059182
  3. Structural and spectroscopic properties of an aliphatic boronic acid studied by combination of experimental and theoretical methods.  |  Cyrański, MK., et al. 2008. J Chem Phys. 128: 124512. PMID: 18376948
  4. Inhibition studies of soybean (Glycine max) urease with heavy metals, sodium salts of mineral acids, boric acid, and boronic acids.  |  Kumar, S. and Kayastha, AM. 2010. J Enzyme Inhib Med Chem. 25: 646-52. PMID: 20014894
  5. Selected ion monitoring gas chromatography/mass spectrometry using uniformly labelled (13C)glucose for determination of glucose turnover in man.  |  Pickert, A., et al. 1991. Biol Mass Spectrom. 20: 203-9. PMID: 2054393
  6. Primary alkylboronic acids as highly active catalysts for the dehydrative amide condensation of α-hydroxycarboxylic acids.  |  Yamashita, R., et al. 2013. Org Lett. 15: 3654-7. PMID: 23802908
  7. First iron and cobalt(II) hexabromoclathrochelates: structural, magnetic, redox, and electrocatalytic behavior.  |  Dolganov, AV., et al. 2015. Dalton Trans. 44: 2476-87. PMID: 25559125
  8. Simultaneous Enantioseparation of Aldohexoses and Aldopentoses Derivatized With L-Tryptophanamide by Reversed Phase HPLC Using Butylboronic Acid as a Complexation Reagent of Monosaccharides.  |  Shou, M., et al. 2015. Chirality. 27: 417-21. PMID: 25994510
  9. Identification of 17 alpha,20 alpha-dihydroxyprogesterone in testicular extracts after incubation with ketoconazole.  |  Lauwers, WF., et al. 1985. Biomed Mass Spectrom. 12: 296-301. PMID: 3160407
  10. Isomeric prostaglandin F2 compounds arising from prostaglandin D2: a family of icosanoids produced in vivo in humans.  |  Wendelborn, DF., et al. 1988. Proc Natl Acad Sci U S A. 85: 304-8. PMID: 3422430
  11. An improved procedure for the determination of ethylene glycol in blood.  |  McCurdy, HH. and Solomons, ET. 1982. J Anal Toxicol. 6: 253-4. PMID: 7176557
  12. The effect of organic solvents on the determination of cyclic boronates of some beta-blockers by gas chromatography/mass spectrometry.  |  Lee, J., et al. 1998. Rapid Commun Mass Spectrom. 12: 1150-60. PMID: 9737006
  13. A new system for catalytic enantioselective reduction of achiral ketones to chiral alcohols. Synthesis of chiral α-hydroxy acids  |  E.J Corey, Raman K Bakshi. 1990. Tetrahedron Letters. 31: 611-614.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Butylboronic acid, 1 g

sc-252528
1 g
$28.00

Butylboronic acid, 5 g

sc-252528A
5 g
$67.00