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Butylated hydroxytoluene (BHT) (CAS 128-37-0)

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Alternate Names:
Butylhydroxytoluene; 2,6-Di-tert-butyl-p-cresol; Dibunol; BHT
Application:
Butylated hydroxytoluene (BHT) is an antioxidant shown to be chemopreventive against a variety of carcinogens
CAS Number:
128-37-0
Purity:
>98%
Molecular Weight:
220.35
Molecular Formula:
C15H24O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Butylated hydroxytoluene (BHT) is an antioxidant shown to be chemopreventive against a variety of carcinogens. As an antioxidant, Butylated hydroxytoluene (BHT) acts as a free radical scavenger, binding to and neutralizing these highly reactive molecules in the body. By doing so, it helps protect cells from damage and reduces oxidative stress, which can otherwise lead to cell damage.


Butylated hydroxytoluene (BHT) (CAS 128-37-0) References

  1. Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant food additives.  |  Williams, GM., et al. 1999. Food Chem Toxicol. 37: 1027-38. PMID: 10541460
  2. Review of the mutagenicity/genotoxicity of butylated hydroxytoluene.  |  Bomhard, EM., et al. 1992. Mutat Res. 277: 187-200. PMID: 1381049
  3. Butylated hydroxytoluene inactivated lipid-containing viruses.  |  Snipes, W., et al. 1975. Science. 188: 64-6. PMID: 163494
  4. Protective role of butylated hydroxytoluene and certain carotenoids in photocarcinogenesis.  |  Black, HS. and Mathews-Roth, MM. 1991. Photochem Photobiol. 53: 707-16. PMID: 1881965
  5. Modulation by butylated hydroxytoluene of liver and bladder carcinogenesis induced by chronic low-level exposure to 2-acetylaminofluorene.  |  Williams, GM., et al. 1991. Cancer Res. 51: 6224-30. PMID: 1933882
  6. Understanding the chemistry behind the antioxidant activities of butylated hydroxytoluene (BHT): a review.  |  Yehye, WA., et al. 2015. Eur J Med Chem. 101: 295-312. PMID: 26150290
  7. Metabolism and pulmonary toxicity of butylated hydroxytoluene (BHT).  |  Witschi, H., et al. 1989. Pharmacol Ther. 42: 89-113. PMID: 2657809
  8. Butylated hydroxytoluene induces astaxanthin and lipid production in Haematococcus pluvialis under high-light and nitrogen-deficiency conditions.  |  Zhao, Y., et al. 2018. Bioresour Technol. 266: 315-321. PMID: 29982053
  9. Exposure to butylated hydroxytoluene compromises endometrial decidualization during early pregnancy.  |  Sun, Z., et al. 2021. Environ Sci Pollut Res Int. 28: 42024-42036. PMID: 33792845
  10. A comparison of cell death mechanisms of antioxidants, butylated hydroxyanisole and butylated hydroxytoluene.  |  Mizobuchi, M., et al. 2022. Drug Chem Toxicol. 45: 1899-1906. PMID: 34013795
  11. SCCS scientific opinion on Butylated hydroxytoluene (BHT) - SCCS/1636/21.  |  , ., et al. 2023. Regul Toxicol Pharmacol. 138: 105312. PMID: 36565917
  12. Review: putative mutagens and carcinogens in foods. III. Butylated hydroxytoluene (BHT).  |  Malkinson, AM. 1983. Environ Mutagen. 5: 353-62. PMID: 6343068
  13. Reactivity of butylated hydroxytoluene.  |  Lambert, CR., et al. 1996. Free Radic Biol Med. 21: 395-400. PMID: 8855452

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Butylated hydroxytoluene (BHT), 100 g

sc-204659
100 g
$62.00

Butylated hydroxytoluene (BHT), 500 g

sc-204659A
500 g
$92.00