Date published: 2025-10-13

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Butyl Paraben (CAS 94-26-8)

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Alternate Names:
Butyl 4-hydroxybenzoate; p-Hydroxybenzoic acid n-butyl ester
Application:
Butyl Paraben is antimicrobial agent used in cosmetic products
CAS Number:
94-26-8
Purity:
99%
Molecular Weight:
194.23
Molecular Formula:
C11H14O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Butyl Paraben, also known as BP, serves as a widely utilized preservative found in various products such as cosmetics, food and beverages, and medical devices. This odorless and tasteless, white crystalline powder belongs to the paraben family, which comprises esters of p-hydroxybenzoic acid. Butyl Paraben acts as a preservative by inhibiting the growth of bacteria, fungi, and other microorganisms. The precise mechanism of action of butyl paraben remains incompletely understood. It is believed to function as an endocrine disruptor by interfering with the activity of enzymes involved in the synthesis of steroid hormones.


Butyl Paraben (CAS 94-26-8) References

  1. Effects of butyl paraben on the male reproductive system in mice.  |  Oishi, S. 2002. Arch Toxicol. 76: 423-9. PMID: 12111007
  2. Higher levels of ethyl paraben and butyl paraben in rat amniotic fluid than in maternal plasma after subcutaneous administration.  |  Frederiksen, H., et al. 2008. Toxicol Sci. 106: 376-83. PMID: 18713765
  3. Butyl paraben-induced changes in DNA methylation in rat epididymal spermatozoa.  |  Park, CJ., et al. 2012. Andrologia. 44 Suppl 1: 187-93. PMID: 21592178
  4. Photosonochemical degradation of butyl-paraben: optimization, toxicity and kinetic studies.  |  Daghrir, R., et al. 2014. Sci Total Environ. 490: 223-34. PMID: 24858220
  5. Effect of butyl paraben on the development and microbial composition of periphyton.  |  Song, C., et al. 2016. Ecotoxicology. 25: 342-9. PMID: 26590928
  6. Butyl paraben and propyl paraben modulate bisphenol A and estradiol concentrations in female and male mice.  |  Pollock, T., et al. 2017. Toxicol Appl Pharmacol. 325: 18-24. PMID: 28390971
  7. Butyl paraben promotes apoptosis in human trophoblast cells through increased oxidative stress-induced endoplasmic reticulum stress.  |  Yang, C., et al. 2018. Environ Toxicol. 33: 436-445. PMID: 29319206
  8. In vitro genotoxic and cytotoxic effects of some paraben esters on human peripheral lymphocytes.  |  Güzel Bayülken, D. and Ayaz Tüylü, B. 2019. Drug Chem Toxicol. 42: 386-393. PMID: 29681198
  9. Assessment of hepatotoxicity and dermal toxicity of butyl paraben and methyl paraben using HepG2 and HDFn in vitro models.  |  Kizhedath, A., et al. 2019. Toxicol In Vitro. 55: 108-115. PMID: 30572011
  10. Maternal paraben exposure triggers childhood overweight development.  |  Leppert, B., et al. 2020. Nat Commun. 11: 561. PMID: 32047148
  11. Electrochemical oxidation of butyl paraben on boron doped diamond in environmental matrices and comparison with sulfate radical-AOP.  |  Pueyo, N., et al. 2020. J Environ Manage. 269: 110783. PMID: 32430283
  12. Prenatal Exposure to Butyl Paraben Is Associated With Fat Percentage in 7-Year-Old Boys.  |  Højsager, FD., et al. 2021. J Clin Endocrinol Metab. 106: e2633-e2638. PMID: 33720358
  13. HPLC method development/validation and skin diffusion study of caffeine, methyl paraben and butyl paraben as skin-diffusing model drugs.  |  Mansour, RSH., et al. 2021. PLoS One. 16: e0247879. PMID: 33730060
  14. Chronic exposure to butyl-paraben causes photosensitivity disruption and memory impairment in adult zebrafish.  |  Kim, JL., et al. 2022. Aquat Toxicol. 251: 106279. PMID: 36044784
  15. New insights on the binding of butyl-paraben to trypsin: experimental and computational approaches.  |  Mostafavi, ES., et al. 2022. J Biomol Struct Dyn. 1-13. PMID: 36510660

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Butyl Paraben, 1 g

sc-210978
1 g
$173.00