Butenafine Hydrochloride (CAS 101827-46-7)

Butenafine hydrochloride is a synthetic benzylamine compound distinguished by its chlorinated double-bond structural element which significantly contributes to its chemical and biological activity, particularly in non-medical research contexts focusing on biochemistry and agriscience. The mode of action of butenafine hydrochloride involves inhibiting the enzyme squalene epoxidase, which is crucial in the sterol biosynthesis pathway in fungi. This inhibition leads to a deficiency in ergosterol, a vital component of fungal cell membranes, and an accumulation of squalene, resulting in fungal cell dysfunction and eventual cell death. In research environments, butenafine hydrochloride has been extensively utilized to study its biochemical behavior and the molecular mechanism underlying its fungicidal activity. This research is particularly relevant in understanding the resistance mechanisms of fungi against similar compounds, helping to inform the development of more effective fungicidal agents and management practices in agriculture. Additionally, its role in disrupting fungal cell growth has been explored in various environmental science studies, assessing its impact and degradation in soil and water systems, thereby contributing to a broader understanding of environmental safety and ecological impacts of fungicidal residues.