Burimamide oxalate CAS: 34970-69-9
MF: C9H16N4S•C2H2O4
MW: 302.35
A mixed H2/H3 antagonist.

Burimamide oxalate (CAS 34970-69-9)

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Synonym: N-[4-(1H-Imidazol-4-yl)butyl]-N'-met hylthiourea oxalate
Application: A mixed H2/H3 antagonist
CAS Number: 34970-69-9
Molecular Weight: 302.35
Molecular Formula: C9H16N4S•C2H2O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Burimamide oxalate is a mixed Histamine H3 Receptor and Histamine H2 Receptor(H2/H3) antagonist. In SK-N-MC cells, this compound displays partial agonist activity. Burimamide oxalate also produces antinicoceptive effects.


References

1. Lamberti, C., et al. 1996. Pharmacol. Biochem. Behav. 53: 567-574. PMID: 8866956
2. Hough, L.B., et al. 2000. Pharmacol. Biochem. Behav. 65: 61-66. PMID: 10638637
3. Wieland, K., et al. 2001. J. Pharmacol. Exp. Ther. 299: 908-914. PMID: 11714875

Physical State :
Solid
Solubility :
Soluble in water (100 mM), and DMSO (100 mM).
Storage :
Desiccate at 4° C
Refractive Index :
n20D 1.59 (Predicted)
Ki Data :
Histamine H4 Receptor: Ki= 39.81 nM (human); Histamine H3 Receptor: Ki= 70 nM; Histamine H1 Receptor: Ki= 290 µM; Histamine H2 Receptor: Ki= 3.98 µM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
56972195
MDL Number :
MFCD09038550
SMILES :
CNC(=S)NCCCCC1=CN=CN1.C(=O)(C(=O)O)O

Download SDS (MSDS)

Certificate of Analysis

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