BUP-1 Antibody (A-3): sc-374345
- BUP-1 Antibody (A-3) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 277-311 within an internal region of BUP-1 of human origin
- recommended for detection of BUP-1 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for BUP-1 Antibody (A-3) for WB applications. These reagents are now offered in bundles with BUP-1 Antibody (A-3) (see ordering information below).
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SEE ALSO...
BUP-1 Antibody (A-3) is a mouse monoclonal IgG1 antibody that detects BUP-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BUP-1, also known as β-ureidopropionase or N-carbamyl-β-alanine amidohydrolase, plays a crucial role in the catabolism of pyrimidines, specifically catalyzing the hydrolysis of N-carbamyl-β-aminoisobutyric acid to produce β-aminoisobutyric acid, ammonia, and carbon dioxide. This enzymatic activity is vital for the proper degradation of thymine and uracil, and any deficiency in BUP-1 can lead to the accumulation of toxic metabolites such as N-carbamyl-β-aminoisobutyric acid and N-carbamyl-β-alanine, which have been associated with abnormal neurological activity. The localization of BUP-1 in the cytoplasm of liver and kidney cells underscores its importance in metabolic processes, as these organs are key players in the regulation of nitrogenous waste and amino acid metabolism. Anti-BUP-1 antibody (A-3) is an essential tool for researchers studying metabolic disorders and the biochemical pathways involving pyrimidine degradation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BUP-1 Antibody (A-3) | sc-374345 | 200 µg/ml | $322.00 | |||
BUP-1 Antibody (A-3): m-IgG Fc BP-HRP Bundle | sc-540441 | 200 µg Ab; 10 µg BP | $361.00 | |||
BUP-1 Antibody (A-3): m-IgG1 BP-HRP Bundle | sc-542124 | 200 µg Ab; 20 µg BP | $361.00 | |||
BUP-1 (A-3) Neutralizing Peptide | sc-374345 P | 100 µg/0.5 ml | $69.00 |