Bumetanide-d5 (CAS 1216739-35-3)
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Bumetanide-d5 is a deuterated version of bumetanide. The presence of deuterium atoms can slow down the metabolic degradation of the molecule, allowing researchers to more accurately track its distribution, interaction, and elimination in biological systems. Bumetanide-d5, serves as a powerful tool in scientific studies, particularly in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, where the distinct signatures of deuterium allow for precise differentiation between the deuterated compound and its non-deuterated counterpart. This capability is invaluable in kinetic studies, where understanding the behavior of a compound is crucial. Bumetanide is an inhibitor of NKCC.
Bumetanide-d5 (CAS 1216739-35-3) References
- Contribution of Monocarboxylate Transporter 6 to the Pharmacokinetics and Pharmacodynamics of Bumetanide in Mice. | Jones, RS., et al. 2020. Drug Metab Dispos. 48: 788-795. PMID: 32587098
- UHPLC-HRMS Method for the Simultaneous Screening of 235 Drugs in Capillary Blood for Doping Control Purpose: Comparative Evaluation of Volumetric and Non-volumetric Dried Blood Spotting Devices. | Mazzarino, M., et al. 2022. ACS Omega. 7: 31845-31868. PMID: 36119994
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bumetanide-d5, 1 mg | sc-217800 | 1 mg | $377.00 | |||
Bumetanide-d5, 10 mg | sc-217800A | 10 mg | $2866.00 |