BTT 3033 (CAS 1259028-99-3)
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BTT 3033 is a potent and selective small molecule inhibitor that targets the YAP-TEAD protein-protein interaction, a pivotal component of the Hippo signaling pathway. This pathway plays a role in the regulation of organ size, tissue homeostasis, and cell proliferation by controlling the transcriptional activity of YAP, a transcriptional coactivator. By inhibiting the YAP-TEAD interaction, BTT 3033 effectively disrupts this signaling cascade, leading to a decrease in the transcription of genes involved in cell proliferation and survival. This mechanism of action makes BTT 3033 useful for research into the molecular underpinnings of cancer, as aberrations in the Hippo pathway are frequently associated with tumorigenesis and cancer progression. Its selective inhibition of the YAP-TEAD interaction provides a precise method for studying the pathway′s role in these processes, facilitating the exploration of potential targets for novel cancer therapies.
BTT 3033 (CAS 1259028-99-3) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BTT 3033, 10 mg | sc-504324 | 10 mg | $592.00 |