BTEB2 Antibody (10B3): sc-69906
- BTEB2 Antibody (10B3) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µl ascites
- raised against BTEB2
- recommended for detection of BTEB2 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for BTEB2 Antibody (10B3). This work is in progress.
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BTEB2 Antibody (10B3) is a mouse monoclonal IgG1 antibody that detects BTEB2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-BTEB2 antibody (10B3) is available in a non-conjugated form, allowing for versatile experimental use. BTEB2, a member of the C2H2 zinc finger family, plays a crucial role in gene regulation by binding to GC-rich motifs found in gene promoters, which can lead to either the activation or repression of transcriptional activities. BTEB2 is particularly important in vascular biology, as BTEB2 is expressed in the fetal aorta and is a target for early growth response protein 1 (Egr-1). BTEB2 expression is notably activated by mitogen-activated protein kinase pathways, highlighting BTEB2′s involvement in cellular responses to growth factors. Additionally, BTEB2 expression is induced in the neointima following vascular injury, indicating BTEB2′s role in the phenotypic modulation of vascular smooth muscle cells in response to mitogen stimulation. Understanding BTEB2′s function and regulatory mechanisms is essential for elucidating BTEB2′s contributions to vascular development and pathology, making BTEB2 monoclonal antibody (10B3) a valuable tool for researchers studying these processes.
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BTEB2 Antibody (10B3) References:
- Inducible expression of basic transcription factor-binding protein 2 (BTEB2), a member of zinc finger family of transcription factors, in cardiac allograft vascular disease. | Ogata, T., et al. 2000. Transplantation. 70: 1653-6. PMID: 11152229
- Transcriptional regulation of vascular smooth muscle cell phenotype. | Walsh, K. and Takahashi, A. 2001. Z Kardiol. 90 Suppl 3: 12-6. PMID: 11374024
- Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling. | Shindo, T., et al. 2002. Nat Med. 8: 856-63. PMID: 12101409
- Smooth muscle cell outgrowth from coronary atherectomy specimens in vitro is associated with less time to restenosis and expression of a key Transcription factor KLF5/BTEB2. | Sakamoto, H., et al. 2003. Cardiology. 100: 80-5. PMID: 14557694
- Intestinal tumor progression is associated with altered function of KLF5. | Bateman, NW., et al. 2004. J Biol Chem. 279: 12093-101. PMID: 14726538
- Overexpression of Kruppel-like factor 5 in esophageal epithelia in vivo leads to increased proliferation in basal but not suprabasal cells. | Goldstein, BG., et al. 2007. Am J Physiol Gastrointest Liver Physiol. 292: G1784-92. PMID: 17395897
- Krüppel-like factor 5 controls keratinocyte migration via the integrin-linked kinase. | Yang, Y., et al. 2008. J Biol Chem. 283: 18812-20. PMID: 18450752
- BTEB2 prevents neuronal apoptosis via promoting bad phosphorylation in rat intracerebral hemorrhage model. | Liu, X., et al. 2015. J Mol Neurosci. 55: 206-216. PMID: 24770868
- Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes. | Ivy, JR., et al. 2015. PLoS One. 10: e0134620. PMID: 26301956
- BTEB2-Activated lncRNA TSPEAR-AS2 Drives GC Progression through Suppressing GJA1 Expression and Upregulating CLDN4 Expression. | Ma, ZH., et al. 2020. Mol Ther Nucleic Acids. 22: 1129-1141. PMID: 33294297
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BTEB2 Antibody (10B3) | sc-69906 | 100 µl ascites | $322.00 |