Molecular structure of BTCP maleate, CAS Number: 112726-66-6
BTCP maleate (CAS 112726-66-6)
Application:
BTCP maleate is a PCP analog and DAT inhibitor
CAS Number:
112726-66-6
Purity:
≥98%
Molecular Weight:
415.6
Molecular Formula:
C19H25NS•C4H4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
BTCP maleate, a compound that differs from phencyclidine by containing a benzothiophenyl group instead of a phenyl ring, is a potent DAT (dopamine transporter) inhibitor. BTCP maleate competitively inhibits the binding of PCP to PCP receptors in the rat cerebellum. Studies suggest that this agent also protects dopaminergic neurons against neurotoxins.
BTCP maleate (CAS 112726-66-6) References
- Conformational preferences of the potent dopamine reuptake blocker BTCP and its analogs and their incorporation into a pharmacophore model. | Froimowitz, M., et al. 2000. J Comput Aided Mol Des. 14: 135-46. PMID: 10721502
- BTCP is a potent reinforcer in rats: comparison of behavior maintained on fixed- and progressive-ratio schedules. | Martin-Fardon, R. and Weiss, F. 2002. Pharmacol Biochem Behav. 72: 343-53. PMID: 11900805
- Differential interaction of phencyclidine-like drugs with the dopamine uptake complex in vivo. | Maurice, T., et al. 1991. J Neurochem. 56: 553-9. PMID: 1671086
- [3H]N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine ([3H]BTCP): a new phencyclidine analog selective for the dopamine uptake complex. | Vignon, J., et al. 1988. Eur J Pharmacol. 148: 427-36. PMID: 3384005
Inhibitor of:
DAT.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BTCP maleate, 10 mg | sc-200397 | 10 mg | $125.00 | |||
BTCP maleate, 50 mg | sc-200397A | 50 mg | $560.00 |