BTA-1 MF: C14H12N2S
MW: 240.3
A fluorescent Thioflavin-T derivative that shows great affinity for amyloid deposits.

BTA-1

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 107ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Alternate Names: 2-(4′-Methylaminophenyl)benzothiazole
Application: BTA-1 is a fluorescent Thioflavin-T derivative that shows great affinity for amyloid deposits
Molecular Weight: 240.3
Molecular Formula: C14H12N2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

BTA-1 is a fluorescent Thioflavin-T derivative that exhibits greater affinity than Thioflavin-T and shows great affinity for amyloid deposits. BTA-1 may cross the blood brain barrier.


References

Klunk, W.E., et al. 2003. J. Neurosci. 23, 2086. Mathis, C.A., et al. 2002. Bioorg. Med. Chem. Lett. 12, 295. Klunk, W.E., et al. 2001. Life Sci. 69, 1471.

Physical State :
Solid
Solubility :
Soluble in DMSO (~10 mg/mL).
Storage :
Store at 4° C
Melting Point :
153.83° C (Predicted)
Boiling Point :
415.54° C at 760 mmHg (Predicted)
Density :
1.26 g/cm3 (Predicted)
Refractive Index :
n20D 1.71 (Predicted)
Ki Data :
Aβ 40: Ki= 11 nM; binding affinity to Beta amyloid aggregates : Ki= 1.28 nM
Fluoresence :
λex ~750 nm, λem ~380-480 nm
pK Values :
pKb: 2.58 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
9837643
MDL Number :
MFCD04974146
SMILES :
CNC1=CC=C(C=C1)C2=NC3=CC=CC=C3S2

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 119ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 11ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.